Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 9/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 9/20 | 0.42 |
| ▸ | PDE5A | O76074 | 7/20 | 0.42 |
| ▸ | PDE4A | P27815 | 7/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.42 |
| ▸ | PDE1A | P54750 | 9/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 9/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 9/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10132788 | 0.90 | PDE5A (0.38) | PDE3BPDE3APDE5APDE4APDE4B | |
| SCHEMBL10162955 | 0.83 | PDE3B (0.39) | PDE3BPDE3APDE5APDE4APDE4B | |
| SCHEMBL10132758 | 0.81 | PDE3B (0.43) | PDE3BPDE3APDE5APDE4APDE4B | |
| SCHEMBL10163166 | 0.79 | TUBB4A (0.42) | KMT2ANPSR1TP53TUBB4ATUBB | |
| SCHEMBL10132857 | 0.78 | NPSR1 (0.38) | PDE3BPDE3APDE5APDE4APDE4B | |
| SCHEMBL10163248 | 0.77 | TUBB4A (0.41) | KMT2ANPSR1TP53TUBB4ATUBB | |
| SCHEMBL10132696 | 0.77 | TUBB4A (0.41) | NPSR1TP53TUBB4ATUBBTUBA3C | |
| SCHEMBL10163168 | 0.76 | GAA (0.39) | PDE3BPDE3APDE1APDE1BPDE1C | |
| SCHEMBL10132643 | 0.76 | TUBB4A (0.40) | KMT2ANPSR1TP53TUBB4ATUBB | |
| SCHEMBL10163179 | 0.75 | TUBB4A (0.41) | KMT2ANPSR1TP53TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741917-B2 | Benzo [C] phenanthridines as antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-06-03 | — | — | US | disclosed |
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUGTERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | CCNT1, XPO4, XDH | PDE3B 2429/4885PDE3A 3139/4885PDE5A 3412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.