SCHEMBL1013283

SCHEMBL1013283

NC(C=O)Cc1ccc(O)cc1

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.55
SLC6A2 P23975 1/20 0.55
SLC7A5 Q01650 1/20 0.55
ESR1 P03372 4/20 0.44
ESR2 Q92731 4/20 0.44
ABAT P80404 1/20 0.43
OPRK1 P41145 1/20 0.42
CA2 P00918 1/20 0.42
HDAC8 Q9BY41 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1013284 1.00 TAAR1 (0.55) TAAR1SLC6A2SLC7A5ESR1ESR2
SCHEMBL1013285 1.00 TAAR1 (0.55) TAAR1SLC6A2SLC7A5ESR1ESR2
Hydrochloric Acid SCHEMBL7870676 0.98 TAAR1 (0.53) TAAR1SLC6A2SLC7A5ESR1ESR2
SCHEMBL9000001 0.98 TAAR1 (0.53) TAAR1SLC6A2SLC7A5ESR1ESR2
SCHEMBL4623579 0.83 CA12 (0.41) TAAR1SLC6A2SLC7A5CA2
SCHEMBL15951403 0.83 TAAR1 (0.59) TAAR1SLC6A2SLC7A5ESR1ESR2
SCHEMBL8855721 0.83 TSHR (0.39) TAAR1SLC6A2SLC7A5CA2
SCHEMBL2269394 0.81 CYP3A4 (0.42) TAAR1SLC7A5CA2
SCHEMBL242931 0.81 CYP3A4 (0.42) TAAR1SLC7A5CA2
SCHEMBL6670843 0.81 HRH3 (0.48) TAAR1SLC6A2ABATCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167109-A1 Aminopiperidine Amides, Derivatives, Compositions, and Uses Related to CXCR4 Modulation UNIV EMORY (US) 2023-06-01 US claimed
WO-2021217143-A1 AMINOPIPERIDINE AMIDES, DERIVATIVES, COMPOSITIONS, AND USES RELATED TO CXCR4 MODULATION EMORY UNIVERSITY (US) 2021-10-28 WO claimed
EP-3725797-B1 STABILIZED LIQUID ENZYME COMPOSITIONS NOVOZYMES AS (DK) 2026-05-06 EP disclosed
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 EP disclosed
US-20230210110-A1 METHOD FOR INDUCING ENVIRONMENTAL STRESS TOLERANCE IN PLANTS AJINOMOTO CO., INC. (JP) 2023-07-06 US disclosed
WO-2023106897-A1 NOVEL PEPTIDE DERIVATIVE DERIVED FROM ADIPONECTIN AND USE THEREOF 서울대학교병원 2023-06-15 WO disclosed
US-20230167109-A1 Aminopiperidine Amides, Derivatives, Compositions, and Uses Related to CXCR4 Modulation UNIV EMORY (US) 2023-06-01 US disclosed
EP-4169381-A1 METHOD FOR INDUCING ENVIRONMENTAL STRESS TOLERANCE IN PLANTS AJINOMOTO CO., INC. (JP) 2023-04-26 EP disclosed
CN-107090014-B Stabilized liquid enzyme compositions 诺维信公司 2023-04-25 CN disclosed
US-11573224-B2 Methods of detection using X-ray fluorescence ICAGEN, LLC (US) 2023-02-07 US disclosed
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed
EP-0585412-A1 INCREASING BLOOD-BRAIN BARRIER PERMEABILITY WITH PERMEABILIZER PEPTIDES ALKERMES, INC. (US) 1994-03-09 EP disclosed
WO-1994001113-A1 OXYTOCIN ANTAGONIST OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1994-01-20 WO disclosed
US-5225402-A Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-07-06 US disclosed
WO-1992018529-A1 INCREASING BLOOD-BRAIN BARRIER PERMEABILITY WITH PERMEABILIZER PEPTIDES ALKERMES, INC. (US) 1992-10-29 WO disclosed
EP-0199085-B1 JOMOL, ITS DERIVATIVES, PROCESS FOR THE PREPARATION OF THESE SUBSTANCES, THEIR USE AND THEIR PRODUCTION Ehrenfeld, Udo, Dr. (DE) 1992-07-08 EP disclosed
US-5116614-A JOMOL DERIVATIVES AS AGENTS FOR THE USE IN MALIGNANT TUMORS AND LOWERED IMMUNE DEFENSES EHRENFELD UDO (DE) 1992-05-26 US disclosed
US-5053216-A Diagnosis,therapy of malignant tumors EHRENFELD UDO (DE) 1991-10-01 US disclosed
EP-0382185-A2 Carbostyril derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-08-16 EP disclosed
EP-0199085-A2 Jomol, its derivatives, process for the preparation of these substances, their use and their production Ehrenfeld, Udo, Dr. (DE) 1986-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167109-A1 Aminopiperidine Amides, Derivatives, Compositions, and Uses Related to CXCR4 Modulation CXCR4, CXCR2, CXCL12 TAAR1 375/4885SLC6A2 691/4885SLC7A5 2223/4885
US-20230210110-A1 METHOD FOR INDUCING ENVIRONMENTAL STRESS TOLERANCE IN PLANTS DAO, ALAD, BCAT1 TAAR1 181/4885SLC6A2 313/4885SLC7A5 315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.