Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | PTDSS1 | P48651 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13240036 | 0.80 | L3MBTL1 (0.68) | L3MBTL1ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL10310318 | 0.79 | L3MBTL1 (0.60) | L3MBTL1ALDH1A1LMNASMN1; SMN2ALPL | |
| SCHEMBL13240026 | 0.78 | L3MBTL1 (0.65) | L3MBTL1ALDH1A1LMNASMN1; SMN2ALPL | |
| SCHEMBL2949815 | 0.78 | L3MBTL1 (0.65) | L3MBTL1ALDH1A1LMNASMN1; SMN2BTK | |
| SCHEMBL13240038 | 0.77 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1LMNASMN1; SMN2ALPL | |
| SCHEMBL2950529 | 0.77 | ALDH1A1 (0.65) | L3MBTL1ALDH1A1LMNASMN1; SMN2ALPL | |
| SCHEMBL2950810 | 0.77 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1LMNASMN1; SMN2ALPL | |
| SCHEMBL27589523 | 0.76 | L3MBTL1 (0.63) | L3MBTL1ALDH1A1LMNASMN1; SMN2HTR2A | |
| SCHEMBL2950498 | 0.76 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2957431 | 0.76 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1LMNASMN1; SMN2ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8115027-B2 | NPY Y5 antagonist | SHIONOGI & CO., LTD. (JP) | 2012-02-14 | — | — | US | disclosed |
| US-20110039802-A1 | NPY Y5 ANTAGONIST | KAWANISHI YASUYUKI | 2011-02-17 | — | — | US | disclosed |
| US-20100292500-A1 | NPY Y5 ANTAGONIST | KAWANISHI YASUYUKI | 2010-11-18 | — | — | US | disclosed |
| US-7781461-B2 | NPY Y5 antagonist | KAWANISHI YASUYUKI | 2010-08-24 | — | — | US | disclosed |
| US-7265130-B2 | NPY Y5 antagonist | SHIONOGI & CO., LTD. (JP) | 2007-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292500-A1 | NPY Y5 ANTAGONIST | NPY5R, NPY1R, NPY2R | L3MBTL1 2541/4885ALDH1A1 4599/4885PTDSS1 2808/4885 |
| US-20110039802-A1 | NPY Y5 ANTAGONIST | NPY5R, NPY1R, NPY2R | L3MBTL1 3389/4885ALDH1A1 4517/4885PTDSS1 2980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.