SCHEMBL10133796

SCHEMBL10133796

Cc1ccc2c(c1)Oc1cc(C34CC5CC(CC(C5)C3)C4)ccc1N2C

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 5/20 0.44
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
GAA P10253 2/20 0.42
POLB P06746 1/20 0.42
GFER P55789 1/20 0.42
LMNA P02545 3/20 0.38
ALDH1A1 P00352 1/20 0.38
KDM4E B2RXH2 1/20 0.36
HSD11B1 P28845 3/20 0.35
NPC1 O15118 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
CNR1 P21554 2/20 0.34
USP2 O75604 1/20 0.33
EPHX2 P34913 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9927344 0.78 NISCH (0.36) MEN1KMT2APOLBLMNAALDH1A1
SCHEMBL13231753 0.72 KDM4E (0.35) MEN1KMT2AGAAALDH1A1KDM4E
SCHEMBL5295731 0.71 LMNA (0.63) MEN1KMT2AGAAPOLBGFER
SCHEMBL15183513 0.71 KDM4E (0.47) GAALMNAALDH1A1KDM4ESMN1; SMN2
SCHEMBL7624085 0.69 MEN1 (0.50) CNR2MEN1KMT2AGAAPOLB
SCHEMBL17430695 0.67 TSHR (0.41) MEN1KMT2AALDH1A1KDM4ENPC1
SCHEMBL26271389 0.66 LMNA (0.41) CNR2MEN1KMT2AGAAPOLB
SCHEMBL24704311 0.65 NISCH (0.33) MEN1KMT2AKDM4ECNR1MAPT
SCHEMBL2763147 0.65 MEN1 (0.55) CNR2MEN1KMT2AGAAPOLB
SCHEMBL2763437 0.65 LMNA (0.77) MEN1KMT2AGAAPOLBGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2439803-B1 PHOTOELECTRIC CONVERSION ELEMENT AND METHOD FOR PRODUCING SAME, PHOTOSENSOR, IMAGING ELEMENT AND METHOD OF DRIVING SAME FUJIFILM CORP (JP) 2017-11-08 EP disclosed
US-20150129861-A1 ORGANIC MATERIAL FOR DEPOSITION, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, DEPOSITION METHOD, AND MANUFACTURING METHOD FOR ORGANIC PHOTOELECTRONIC ONVERSION ELEMENT OBTAINED USING THE SAME FUJIFILM CORPORATION (JP) 2015-05-14 US disclosed
US-20150129861-A1 ORGANIC MATERIAL FOR DEPOSITION, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, DEPOSITION METHOD, AND MANUFACTURING METHOD FOR ORGANIC PHOTOELECTRONIC ONVERSION ELEMENT OBTAINED USING THE SAME FUJIFILM CORPORATION (JP) 2015-05-14 US disclosed
US-8847141-B2 Photoelectric conversion element, production method thereof, photosensor, imaging device and their driving method FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
US-8847141-B2 Photoelectric conversion element, production method thereof, photosensor, imaging device and their driving method FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
US-20140042411-A1 METHOD FOR PURIFYING ORGANIC MATERIAL, MATERIAL FOR ORGANIC ELECTRONICS, PHOTOELECTRIC CONVERSION DEVICE, OPTICAL SENSOR, IMAGING DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2014-02-13 US disclosed
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD FUJIFILM CORPORATION (JP) 2012-04-05 US disclosed
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD FUJIFILM CORPORATION (JP) 2012-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD SUN2, CYBA, PPOX CNR2 3378/4885MEN1 2027/4885KMT2A 2433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.