Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10113721 | 0.88 | ALDH1A1 (0.54) | ALDH1A1LMNAHDAC6MEN1KMT2A | |
| SCHEMBL10115197 | 0.88 | ALDH1A1 (0.68) | ALDH1A1LMNAHDAC6MEN1KMT2A | |
| SCHEMBL10113688 | 0.87 | HDAC3 (0.56) | ALDH1A1LMNAHDAC6MEN1KMT2A | |
| SCHEMBL10115264 | 0.87 | HDAC6 (0.62) | ALDH1A1LMNAHDAC6MEN1KMT2A | |
| SCHEMBL10113680 | 0.87 | ALDH1A1 (0.53) | ALDH1A1LMNAHDAC6MEN1KMT2A | |
| SCHEMBL10115351 | 0.87 | LMNA (0.53) | ALDH1A1LMNAHDAC6MEN1KMT2A | |
| SCHEMBL10115275 | 0.87 | ALDH1A1 (0.54) | ALDH1A1LMNAHDAC6MEN1KMT2A | |
| SCHEMBL10113729 | 0.87 | HDAC6 (0.53) | ALDH1A1LMNAHDAC6MEN1KMT2A | |
| SCHEMBL10113711 | 0.87 | ALDH1A1 (0.53) | ALDH1A1LMNAHDAC6MEN1KMT2A | |
| SCHEMBL10115297 | 0.86 | HDAC6 (0.67) | ALDH1A1LMNAHDAC6HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8115027-B2 | NPY Y5 antagonist | SHIONOGI & CO., LTD. (JP) | 2012-02-14 | — | — | US | disclosed |
| US-20100292500-A1 | NPY Y5 ANTAGONIST | KAWANISHI YASUYUKI | 2010-11-18 | — | — | US | disclosed |
| US-7781461-B2 | NPY Y5 antagonist | KAWANISHI YASUYUKI | 2010-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292500-A1 | NPY Y5 ANTAGONIST | NPY5R, NPY1R, NPY2R | ALDH1A1 4599/4885LMNA 2068/4885HDAC6 1602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.