SCHEMBL10134023

SCHEMBL10134023

CC(=O)Nc1cccc(NC=O)c1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
HSD17B10 Q99714 2/20 0.59
CYP1A2 P05177 1/20 0.59
RAB9A P51151 2/20 0.59
POLB P06746 1/20 0.59
NR4A1 P22736 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.57
TP53 P04637 1/20 0.54
NAPRT Q6XQN6 1/20 0.53
MAPT P10636 1/20 0.53
TSHR P16473 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1901172 0.86 ALDH1A1 (0.76) ALDH1A1HSD17B10CYP1A2RAB9APOLB
SCHEMBL12129057 0.82 ALDH1A1 (0.67) ALDH1A1HSD17B10CYP1A2TP53MAPT
SCHEMBL3901564 0.81 KMT2A (0.60) ALDH1A1CYP1A2RAB9APOLBL3MBTL1
SCHEMBL27392287 0.81 GAA (0.47) ALDH1A1MAPT
SCHEMBL10705800 0.81 TP53 (0.56) TP53TSHR
SCHEMBL1176396 0.80 SMN1; SMN2 (0.61) ALDH1A1HSD17B10RAB9APOLBL3MBTL1
SCHEMBL1487964 0.79 ALDH1A1 (0.66) ALDH1A1HSD17B10CYP1A2RAB9APOLB
SCHEMBL4714652 0.79 HSD17B10 (0.71) ALDH1A1HSD17B10CYP1A2RAB9APOLB
SCHEMBL527866 0.78 ALDH1A1 (0.59) ALDH1A1HSD17B10CYP1A2RAB9APOLB
SCHEMBL19200618 0.77 ALDH1A1 (0.54) ALDH1A1HSD17B10CYP1A2RAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109593384-B Preparation method of pre-dispersed pigment for offset printing ink 宇虹颜料股份有限公司 2020-09-25 CN disclosed
US-9618867-B2 Pigment dispersion and toner CANON KABUSHIKI KAISHA (JP) 2017-04-11 US disclosed
US-8115027-B2 NPY Y5 antagonist SHIONOGI & CO., LTD. (JP) 2012-02-14 US disclosed
US-20100292500-A1 NPY Y5 ANTAGONIST KAWANISHI YASUYUKI 2010-11-18 US disclosed
EP-2014285-A1 NPYY5 antagonists Shionogi&Co., Ltd. (JP) 2009-01-14 EP disclosed
US-7303589-B2 Process for dyeing human keratin fibers, having a lightening effect, comprising at least one fluorescent compound and compositions of the same L'OREAL S.A. (FR) 2007-12-04 US disclosed
US-7265130-B2 NPY Y5 antagonist SHIONOGI & CO., LTD. (JP) 2007-09-04 US disclosed
US-7250064-B2 Dye composition comprising at least one fluorescent dye and a non-associative thickening polymer for human keratin materials, process therefor, and method thereof L'OREAL S.A. (FR) 2007-07-31 US disclosed
US-7208018-B2 Composition for dyeing human keratin materials, comprising at least one fluorescent dye and at least one associative polymer, process therefor and use thereof L'OREAL (FR) 2007-04-24 US disclosed
US-7204860-B2 Composition for dyeing human keratin materials, comprising at least one fluorescent dye and at least one polyol, process therefor and use thereof L'OREAL (FR) 2007-04-17 US disclosed
US-7198650-B2 Method of dyeing human keratin materials with a lightening effect with compositions comprising at least one fluorescent dye and at least one amphoteric or nonionic surfactant, composition thereof, process thereof, and device therefor L'OREAL S.A. (FR) 2007-04-03 US disclosed
EP-1622581-B1 DYEING METHOD FOR HUMAN KERATINOUS FIBERS WITH LIGHTENING EFFECT, PARTICULAR FLUORESCENT COMPOUND AND COMPOSITION COMPRISING SAME OREAL (FR) 2007-03-28 EP disclosed
US-7195651-B2 Cosmetic composition for dyeing human keratin materials, comprising at least one fluorescent dye and at least one cationic polymer, and a dyeing process therefor L'OREAL S.A. (FR) 2007-03-27 US disclosed
US-7195650-B2 Process for dyeing, with a lightening effect, human keratin fibers that have been permanently reshaped, using at least one composition comprising at least one fluorescent dye L'OREAL S.A. (FR) 2007-03-27 US disclosed
US-7192454-B2 Composition for dyeing human keratin materials, comprising a fluorescent dye and a particular sequestering agent, process therefor and use thereof L'OREAL S.A. (FR) 2007-03-20 US disclosed
US-7186278-B2 Composition for dyeing human keratin materials, comprising at least one fluorescent dye and at least one compound comprising an acid functional group and processes therefor L'OREAL S.A. (FR) 2007-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100292500-A1 NPY Y5 ANTAGONIST NPY5R, NPY1R, NPY2R ALDH1A1 4599/4885HSD17B10 1102/4885CYP1A2 1230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.