SCHEMBL10134247

SCHEMBL10134247

CC1(C)c2cc(-c3ccc4c(c3)C(C)(C)c3cc(N5c6ccccc6Oc6ccccc65)ccc3-4)ccc2-c2ccc(N3c4ccccc4Oc4ccccc43)cc21

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 7/20 0.32
MAPT P10636 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
NPSR1 Q6W5P4 1/20 0.31
PDK2 Q15119 2/20 0.31
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
USP2 O75604 1/20 0.30
POLB P06746 1/20 0.30
HTT P42858 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22600945 0.94 PDK2 (0.33) P2RX4MAPTSMN1; SMN2NPSR1PDK2
SCHEMBL3790816 0.94 P2RX4 (0.35) P2RX4MAPTSMN1; SMN2NPSR1MEN1
SCHEMBL14073373 0.91 P2RX4 (0.33) P2RX4MAPTSMN1; SMN2NPSR1MEN1
SCHEMBL22600910 0.91 PGR (0.37) MAPTSMN1; SMN2PDK2MEN1NPC1
SCHEMBL24062410 0.90 PGR (0.38) P2RX4MAPTSMN1; SMN2PDK2MEN1
SCHEMBL18544764 0.88 PGR (0.35) PDK2MEN1KMT2A
SCHEMBL2604409 0.87 PDK2 (0.37) NPSR1PDK2MEN1KMT2A
SCHEMBL12934421 0.87 PGR (0.33) P2RX4PDK2
SCHEMBL2604406 0.85 PDK2 (0.35) PDK2MEN1KMT2A
SCHEMBL12793965 0.85 PDK2 (0.35) PDK2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2439803-B1 PHOTOELECTRIC CONVERSION ELEMENT AND METHOD FOR PRODUCING SAME, PHOTOSENSOR, IMAGING ELEMENT AND METHOD OF DRIVING SAME FUJIFILM CORP (JP) 2017-11-08 EP disclosed
US-8847141-B2 Photoelectric conversion element, production method thereof, photosensor, imaging device and their driving method FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
US-8847141-B2 Photoelectric conversion element, production method thereof, photosensor, imaging device and their driving method FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD FUJIFILM CORPORATION (JP) 2012-04-05 US disclosed
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD FUJIFILM CORPORATION (JP) 2012-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD SUN2, CYBA, PPOX P2RX4 1401/4885MAPT 342/4885SMN1; SMN2 4710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.