SCHEMBL10134261

SCHEMBL10134261

Cc1ccc2c3ccc(-c4ccc5c6ccc(C)cc6n(-c6ccccc6)c5c4)cc3n(-c3ccccc3)c2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.48
ATM Q13315 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
ALDH1A1 P00352 8/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
HPGD P15428 2/20 0.44
AVPR1A P37288 1/20 0.42
GAA P10253 2/20 0.41
MAT2A P31153 1/20 0.40
RXFP1 Q9HBX9 1/20 0.39
FGFR1 P11362 1/20 0.39
LMNA P02545 1/20 0.39
NR1I2 O75469 1/20 0.38
EGFR P00533 1/20 0.38
ADRA2A P08913 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
TBXA2R P21731 1/20 0.38
PTGS2 P35354 1/20 0.38
OPRD1 P41143 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15040915 0.97 AVPR1A (0.47) KDM4EATML3MBTL1ALDH1A1MEN1
SCHEMBL679025 0.93 KDM4E (0.56) KDM4EATML3MBTL1ALDH1A1MEN1
SCHEMBL20412021 0.92 KDM4E (0.46) KDM4EATML3MBTL1ALDH1A1MEN1
SCHEMBL13829477 0.91 CYP2A6 (0.46) KDM4EATML3MBTL1ALDH1A1MEN1
SCHEMBL26323771 0.90 KDM4E (0.47) KDM4EATML3MBTL1ALDH1A1MEN1
SCHEMBL15040913 0.89 KDM4E (0.46) KDM4EATML3MBTL1ALDH1A1MEN1
SCHEMBL19844344 0.89 KDM4E (0.55) KDM4EATML3MBTL1ALDH1A1MEN1
SCHEMBL883711 0.89 KDM4E (0.46) KDM4EATML3MBTL1ALDH1A1MEN1
SCHEMBL19928298 0.89 KDM4E (0.55) KDM4EATML3MBTL1ALDH1A1MEN1
SCHEMBL9917211 0.88 KDM4E (0.58) KDM4EATML3MBTL1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150129861-A1 ORGANIC MATERIAL FOR DEPOSITION, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, DEPOSITION METHOD, AND MANUFACTURING METHOD FOR ORGANIC PHOTOELECTRONIC ONVERSION ELEMENT OBTAINED USING THE SAME FUJIFILM CORPORATION (JP) 2015-05-14 US disclosed
US-8847141-B2 Photoelectric conversion element, production method thereof, photosensor, imaging device and their driving method FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
US-20140042411-A1 METHOD FOR PURIFYING ORGANIC MATERIAL, MATERIAL FOR ORGANIC ELECTRONICS, PHOTOELECTRIC CONVERSION DEVICE, OPTICAL SENSOR, IMAGING DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2014-02-13 US disclosed
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD FUJIFILM CORPORATION (JP) 2012-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD SUN2, CYBA, PPOX KDM4E 169/4885ATM 3891/4885L3MBTL1 4402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.