SCHEMBL15040915

SCHEMBL15040915

Cc1ccc2c3ccc(-c4ccccc4)cc3n(-c3ccccc3)c2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AVPR1A P37288 1/20 0.47
KDM4E B2RXH2 2/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ALDH1A1 P00352 6/20 0.42
HPGD P15428 3/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
NR1I2 O75469 1/20 0.40
EGFR P00533 1/20 0.40
ADRA2A P08913 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
TBXA2R P21731 1/20 0.40
PTGS2 P35354 1/20 0.40
OPRD1 P41143 1/20 0.40
PDE4D Q08499 1/20 0.40
MAOB P27338 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
GAA P10253 2/20 0.39
PPARG P37231 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10134261 0.97 KDM4E (0.48) AVPR1AKDM4EATML3MBTL1ALDH1A1
SCHEMBL883711 0.92 KDM4E (0.46) AVPR1AKDM4EATML3MBTL1ALDH1A1
SCHEMBL15040913 0.92 KDM4E (0.46) AVPR1AKDM4EATML3MBTL1ALDH1A1
SCHEMBL19743197 0.92 ALDH1A1 (0.46) AVPR1AKDM4EATML3MBTL1ALDH1A1
SCHEMBL17032735 0.90 KDM4E (0.49) AVPR1AKDM4EATML3MBTL1ALDH1A1
SCHEMBL679025 0.89 KDM4E (0.56) KDM4EATML3MBTL1ALDH1A1MEN1
SCHEMBL17690019 0.89 ATM (0.56) AVPR1AKDM4EATML3MBTL1ALDH1A1
SCHEMBL17178972 0.89 KDM4E (0.42) AVPR1AKDM4EATML3MBTL1ALDH1A1
SCHEMBL19001868 0.89 KDM4E (0.46) AVPR1AKDM4EATML3MBTL1ALDH1A1
SCHEMBL25622650 0.89 KDM4E (0.42) AVPR1AKDM4EATML3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3670520-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2022-01-12 EP disclosed
US-10941171-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-03-09 US disclosed
EP-3712145-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SUCH COMPOUND Samsung Electronics Co., Ltd. (KR) 2020-09-23 EP disclosed
US-10403833-B2 Organic metal complexes MERCK PATENT GMBH (DE) 2019-09-03 US disclosed
US-20190153008-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-05-23 US disclosed
US-20180130964-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-10 US disclosed
US-9879177-B2 Metal complexes comprising condensed heteroaromatic rings MERCK PATENT GMBH (DE) 2018-01-30 US disclosed
US-9879177-B2 Metal complexes comprising condensed heteroaromatic rings MERCK PATENT GMBH (DE) 2018-01-30 US disclosed
US-20170317298-A1 ORGANIC METAL COMPLEXES UDC IRELAND LIMITED (IE) 2017-11-02 US disclosed
US-20170317298-A1 ORGANIC METAL COMPLEXES UDC IRELAND LIMITED (IE) 2017-11-02 US disclosed
US-20150105843-A1 METAL COMPLEXES COMPRISING CONDENSED HETEROAROMATIC RINGS UDC IRELAND LIMITED (IE) 2015-04-16 US disclosed
US-20140371825-A1 ORGANIC METAL COMPLEXES UDC IRELAND LIMITED (IE) 2014-12-18 US disclosed
US-20140371825-A1 ORGANIC METAL COMPLEXES UDC IRELAND LIMITED (IE) 2014-12-18 US disclosed
US-20140358198-A1 ORGANIC SENSITIZERS FOR UP-CONVERSION MERCK PATENT GMBH (DE) 2014-12-04 US disclosed
US-20140358198-A1 ORGANIC SENSITIZERS FOR UP-CONVERSION MERCK PATENT GMBH (DE) 2014-12-04 US disclosed
US-20140350642-A1 Metal Complexes Comprising 1,2,3-Triazoles MERCK PATENT GMBH (DE) 2014-11-27 US disclosed
US-20140350642-A1 Metal Complexes Comprising 1,2,3-Triazoles MERCK PATENT GMBH (DE) 2014-11-27 US disclosed
WO-2013107487-A1 ORGANIC METAL COMPLEXES MERCK PATENT GMBH (DE) 2013-07-25 WO disclosed
WO-2013097920-A1 METAL COMPLEXES COMPRISING 1,2,3-TRIAZOLES MERCK PATENT GMBH (DE) 2013-07-04 WO disclosed
WO-2013087162-A1 ORGANIC SENSITIZERS FOR UP-CONVERSION MERCK PATENT GMBH (DE) 2013-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10403833-B2 Organic metal complexes SOD1, ORC3, PPIA AVPR1A 2736/4885KDM4E 3392/4885ATM 3876/4885
US-20190153008-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, LEF1, POU2F1 AVPR1A 3629/4885KDM4E 1677/4885ATM 2194/4885
US-20180130964-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING ORGANOMETALLIC COMPOUND ORC3, OCIAD1, LEF1 AVPR1A 4479/4885KDM4E 2792/4885ATM 1634/4885
US-10941171-B2 Organometallic compound and organic light-emitting device including the same CRY1, LEF1, POU2F1 AVPR1A 3629/4885KDM4E 1677/4885ATM 2194/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.