SCHEMBL10134372

SCHEMBL10134372

c1ccc2c(c1)-c1ccccc1N(c1ccc3cc4cc(N5c6ccccc6-c6ccccc6-c6ccccc65)ccc4cc3c1)c1ccccc1-2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.44
ALDH1A1 P00352 4/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 2/20 0.37
LMNA P02545 1/20 0.37
HPGD P15428 1/20 0.37
CES2 O00748 1/20 0.36
BCHE P06276 1/20 0.36
GAA P10253 1/20 0.36
CES1 P23141 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
CYP3A4 P08684 2/20 0.34
ALOX15 P16050 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
HBB P68871 1/20 0.34
HIF1A Q16665 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16490187 0.85 HSP90AA1 (0.38) HSP90AA1ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL16490188 0.83 ALDH1A1 (0.42) HSP90AA1ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL17929867 0.82 HSP90AA1 (0.52) HSP90AA1ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL24254003 0.82 ALDH1A1 (0.52) HSP90AA1ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL16490203 0.82 ALDH1A1 (0.37) HSP90AA1ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL10013271 0.80 ALDH1A1 (0.50) ALDH1A1LMNAHPGDCES2BCHE
SCHEMBL16773383 0.79 ALDH1A1 (0.47) HSP90AA1ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL23331452 0.79 HSP90AA1 (0.41) HSP90AA1ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL65365 0.79 ALDH1A1 (0.45) HSP90AA1ALDH1A1CES2BCHEGAA
SCHEMBL13886639 0.79 HSP90AA1 (0.61) HSP90AA1ALDH1A1CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2439803-B1 PHOTOELECTRIC CONVERSION ELEMENT AND METHOD FOR PRODUCING SAME, PHOTOSENSOR, IMAGING ELEMENT AND METHOD OF DRIVING SAME FUJIFILM CORP (JP) 2017-11-08 EP disclosed
US-8847141-B2 Photoelectric conversion element, production method thereof, photosensor, imaging device and their driving method FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
US-8847208-B2 Photoelectric conversion device and imaging device having decreased dark current FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
US-8847208-B2 Photoelectric conversion device and imaging device having decreased dark current FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
US-8847141-B2 Photoelectric conversion element, production method thereof, photosensor, imaging device and their driving method FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD FUJIFILM CORPORATION (JP) 2012-04-05 US disclosed
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD FUJIFILM CORPORATION (JP) 2012-04-05 US disclosed
US-20100308311-A1 PHOTOELECTRIC CONVERSION DEVICE AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20100308311-A1 PHOTOELECTRIC CONVERSION DEVICE AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD SUN2, CYBA, PPOX HSP90AA1 1008/4885ALDH1A1 1609/4885CYP1A2 166/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.