Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 7/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.54 |
| ▸ | AKR1A1 | P14550 | 2/20 | 0.48 |
| ▸ | CBR1 | P16152 | 2/20 | 0.48 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15298966 | 0.85 | AKR1B10 (0.74) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL47328 | 0.81 | AKR1B10 (0.51) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL19828570 | 0.78 | KMT2A (0.52) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL43817 | 0.77 | AKR1B10 (0.59) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL9303724 | 0.73 | KMT2A (0.70) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL16293207 | 0.73 | KMT2A (0.73) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL13403918 | 0.72 | KMT2A (0.71) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14155417 | 0.72 | KMT2A (0.53) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8398863 | 0.71 | KMT2A (0.60) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL13081989 | 0.70 | KMT2A (0.70) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003476-A2 | HAPTEN CONJUGATES FOR TARGET DETECTION | VENTANA MEDICAL SYSTEMS, INC. (US) | 2012-01-05 | — | — | WO | disclosed |