Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL580009 | 0.79 | MEN1 (0.77) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL29611843 | 0.79 | MEN1 (0.77) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL19828501 | 0.79 | KDM4E (0.58) | KMT2AMEN1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL19828569 | 0.79 | ALDH1A1 (0.54) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10134566 | 0.78 | AKR1B10 (0.54) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14820431 | 0.77 | KMT2A (0.67) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9303724 | 0.76 | KMT2A (0.70) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL16293207 | 0.76 | KMT2A (0.73) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL13081989 | 0.75 | KMT2A (0.70) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL13403918 | 0.75 | KMT2A (0.71) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564674-A1 | HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE | Ventana Medical Systems, Inc. (US) | 2019-11-06 | — | — | EP | disclosed |
| EP-3276349-A1 | HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE | Ventana Medical Systems, Inc. (US) | 2018-01-31 | — | — | EP | disclosed |