Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 8/20 | 0.58 |
| ▸ | CSNK2B | P67870 | 8/20 | 0.58 |
| ▸ | CSNK2A1 | P68400 | 9/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 2/20 | 0.49 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL629013 | 0.90 | CSNK2A2 (0.71) | CSNK2A2CSNK2BCSNK2A1PARP1PIM1 | |
| SCHEMBL2690184 | 0.85 | CSNK2A2 (0.68) | CSNK2A2CSNK2BCSNK2A1PARP1PIM1 | |
| SCHEMBL10134624 | 0.82 | CSNK2A2 (0.51) | CSNK2A2CSNK2BCSNK2A1PARP1PIM1 | |
| SCHEMBL29056046 | 0.82 | CSNK2A1 (0.53) | CSNK2A2CSNK2BCSNK2A1PARP1PIM1 | |
| SCHEMBL30504720 | 0.82 | CSNK2A1 (0.53) | CSNK2A2CSNK2BCSNK2A1PARP1PIM1 | |
| SCHEMBL25251658 | 0.78 | TP53 (0.50) | CSNK2A1ALOX15HTTTP53GAA | |
| SCHEMBL20704185 | 0.78 | HIPK2 (0.68) | CSNK2A2CSNK2BCSNK2A1PARP1CYP19A1 | |
| SCHEMBL16651864 | 0.76 | ALDH1A1 (0.54) | CSNK2A1ALOX15HTTTP53GAA | |
| SCHEMBL8890757 | 0.75 | CSNK2A1 (0.66) | CSNK2A2CSNK2BCSNK2A1PARP1 | |
| SCHEMBL5349000 | 0.74 | CSNK2A1 (0.56) | CSNK2A2CSNK2BCSNK2A1ALOX15HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120208792-A1 | PROTEIN KINASE MODULATORS | CYLENE PHARMACEUTICALS, INC. (US) | 2012-08-16 | — | — | US | disclosed |
| US-8168651-B2 | Protein kinase modulators | CYLENE PHARMACEUTICALS, INC. (US) | 2012-05-01 | — | — | US | disclosed |
| US-8168651-B2 | Protein kinase modulators | CYLENE PHARMACEUTICALS, INC. (US) | 2012-05-01 | — | — | US | disclosed |
| US-20090239859-A1 | PROTEIN KINASE MODULATORS | SENHWA BIOSCIENCES, INC. (TW) | 2009-09-24 | — | — | US | disclosed |
| US-20090239859-A1 | PROTEIN KINASE MODULATORS | SENHWA BIOSCIENCES, INC. (TW) | 2009-09-24 | — | — | US | disclosed |
| WO-2009108912-A1 | PROTEIN KINASE MODULATORS | CYLENE PHARMACEUTICALS, INC. (US) | 2009-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208792-A1 | PROTEIN KINASE MODULATORS | PIM1, PIM2, PIM3 | CSNK2A2 810/4885CSNK2B 772/4885CSNK2A1 680/4885 |
| US-20090239859-A1 | PROTEIN KINASE MODULATORS | PIM1, PIM2, PIM3 | CSNK2A2 810/4885CSNK2B 772/4885CSNK2A1 680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.