SCHEMBL629013

SCHEMBL629013

COC(=O)c1ccc2c(c1)nc(Cl)c1ccncc12

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 15/20 0.71
CSNK2B P67870 15/20 0.71
CSNK2A1 P68400 13/20 0.67
PARP1 P09874 1/20 0.56
CLK2 P49760 4/20 0.49
CSNK2A3 Q8NEV1 4/20 0.49
CHEK1 O14757 1/20 0.48
GAK O14976 1/20 0.48
DAPK3 O43293 1/20 0.48
DYRK3 O43781 1/20 0.48
ULK1 O75385 1/20 0.48
STK10 O94804 1/20 0.48
CCNB2 O95067 1/20 0.48
CDK1 P06493 1/20 0.48
PIM1 P11309 1/20 0.48
CCNB1 P14635 1/20 0.48
PHKG2 P15735 1/20 0.48
CCNE1 P24864 1/20 0.48
CDK2 P24941 1/20 0.48
TYK2 P29597 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2690184 0.95 CSNK2A2 (0.68) CSNK2A2CSNK2BCSNK2A1PARP1CLK2
SCHEMBL10134627 0.90 CSNK2A2 (0.58) CSNK2A2CSNK2BCSNK2A1PARP1PIM1
SCHEMBL8890757 0.86 CSNK2A1 (0.66) CSNK2A2CSNK2BCSNK2A1PARP1
SCHEMBL12824331 0.83 CSNK2A2 (1.00) CSNK2A2CSNK2BCSNK2A1
SCHEMBL10131328 0.82 CSNK2A1 (0.72) CSNK2A2CSNK2BCSNK2A1PARP1PIM1
SCHEMBL10134624 0.82 CSNK2A2 (0.51) CSNK2A2CSNK2BCSNK2A1PARP1PIM1
SCHEMBL1450213 0.81 CSNK2A2 (0.80) CSNK2A2CSNK2BCSNK2A1
SCHEMBL20704185 0.81 HIPK2 (0.68) CSNK2A2CSNK2BCSNK2A1PARP1
SCHEMBL629907 0.80 CSNK2A1 (1.00) CSNK2A2CSNK2BCSNK2A1
SCHEMBL2689292 0.79 CSNK2A1 (0.80) CSNK2A2CSNK2BCSNK2A1CLK2CSNK2A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12383624-B2 Cargo delivery system and composition comprising the same SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2025-08-12 US disclosed
WO-2023126951-A1 INHIBITORS OF AUTOPHAGY-RELATED PROTEIN-PROTEIN INTERACTIONS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2023-07-06 WO disclosed
WO-2023126951-A1 INHIBITORS OF AUTOPHAGY-RELATED PROTEIN-PROTEIN INTERACTIONS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2023-07-06 WO disclosed
US-20230190938-A1 NOVEL CARGO DELIVERY SYSTEM AND COMPOSITION COMPRISING THE SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2023-06-22 US disclosed
US-20230190938-A1 NOVEL CARGO DELIVERY SYSTEM AND COMPOSITION COMPRISING THE SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2023-06-22 US disclosed
US-20230190938-A1 NOVEL CARGO DELIVERY SYSTEM AND COMPOSITION COMPRISING THE SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2023-06-22 US disclosed
US-11071727-B2 Therapeutic targeting of proteolytic cleavage of the mixed lineage leukemia gene product (MLL1) by taspase1 using kinase inhibitors NORTHWESTERN UNIVERSITY (US) 2021-07-27 US disclosed
US-20190231759-A1 THERAPEUTIC TARGETING OF PROTEOLYTIC CLEAVAGE OF THE MIXED LINEAGE LEUKEMIA GENE PRODUCT (MLL1) BY TASPASE1 USING KINASE INHIBITORS NORTHWESTERN UNIVERSITY (US) 2019-08-01 US disclosed
US-9062043-B2 Fused tricyclic compounds as serine-threonine protein kinase and PARP modulators SENHWA BIOSCIENCES, INC. (TW) 2015-06-23 US disclosed
US-9062043-B2 Fused tricyclic compounds as serine-threonine protein kinase and PARP modulators SENHWA BIOSCIENCES, INC. (TW) 2015-06-23 US disclosed
WO-2009097014-A2 THERAPEUTIC KINASE MODULATORS CYLENE PHARMACEUTICALS, INC. (US) 2009-08-06 WO disclosed
EP-2061765-A2 SERINE-THREONINE PROTEIN KINASE AND PARP MODULATORS Cylene Pharmaceuticals, Inc. (US) 2009-05-27 EP disclosed
US-20090105233-A1 SERINE-THREONINE PROTEIN KINASE AND PARP MODULATORS SENHWA BIOSCIENCES, INC. (TW) 2009-04-23 US disclosed
US-20090105233-A1 SERINE-THREONINE PROTEIN KINASE AND PARP MODULATORS SENHWA BIOSCIENCES, INC. (TW) 2009-04-23 US disclosed
US-20090105233-A1 SERINE-THREONINE PROTEIN KINASE AND PARP MODULATORS SENHWA BIOSCIENCES, INC. (TW) 2009-04-23 US disclosed
US-20090093465-A1 THERAPEUTIC KINASE MODULATORS CYLENE PHARMACEUTICALS, INC. (US) 2009-04-09 US disclosed
US-20090093465-A1 THERAPEUTIC KINASE MODULATORS CYLENE PHARMACEUTICALS, INC. (US) 2009-04-09 US disclosed
US-20090093465-A1 THERAPEUTIC KINASE MODULATORS CYLENE PHARMACEUTICALS, INC. (US) 2009-04-09 US disclosed
WO-2008028168-A2 SERINE-THREONINE PROTEIN KINASE AND PARP MODULATORS CYLENE PHARMACEUTICALS, INC. (US) 2008-03-06 WO disclosed
WO-2008028168-A2 SERINE-THREONINE PROTEIN KINASE AND PARP MODULATORS CYLENE PHARMACEUTICALS, INC. (US) 2008-03-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190231759-A1 THERAPEUTIC TARGETING OF PROTEOLYTIC CLEAVAGE OF THE MIXED LINEAGE LEUKEMIA GENE PRODUCT (MLL1) BY TASPASE1 USING KINASE INHIBITORS MLLT1, TASP1, MLLT3 CSNK2A2 40/4885CSNK2B 58/4885CSNK2A1 38/4885
US-20230190938-A1 NOVEL CARGO DELIVERY SYSTEM AND COMPOSITION COMPRISING THE SAME ATG7, SQSTM1, BECN1 CSNK2A2 983/4885CSNK2B 952/4885CSNK2A1 956/4885
US-12383624-B2 Cargo delivery system and composition comprising the same ATG7, SQSTM1, BECN1 CSNK2A2 1148/4885CSNK2B 1185/4885CSNK2A1 1104/4885
US-20090093465-A1 THERAPEUTIC KINASE MODULATORS PACSIN2, CKS1B, CSNK1A1 CSNK2A2 11/4885CSNK2B 16/4885CSNK2A1 6/4885
US-20090105233-A1 SERINE-THREONINE PROTEIN KINASE AND PARP MODULATORS PACSIN2, TNKS, PARP1 CSNK2A2 37/4885CSNK2B 39/4885CSNK2A1 24/4885
US-11071727-B2 Therapeutic targeting of proteolytic cleavage of the mixed lineage leukemia gene product (MLL1) by taspase1 using kinase inhibitors MLLT1, TASP1, MLLT3 CSNK2A2 40/4885CSNK2B 58/4885CSNK2A1 38/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.