Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 17/20 | 0.60 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.54 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15383531 | 1.00 | FOLH1 (0.60) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL9912229 | 0.93 | FOLH1 (0.68) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL18253629 | 0.93 | FOLH1 (0.68) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL24123152 | 0.93 | FOLH1 (0.68) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL20910851 | 0.92 | FOLH1 (0.66) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL26758628 | 0.89 | FOLH1 (0.64) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL26757300 | 0.88 | FOLH1 (0.65) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL26757303 | 0.84 | FOLH1 (0.59) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL26757838 | 0.84 | FOLH1 (0.58) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL24491153 | 0.84 | FOLH1 (0.55) | FOLH1NAALAD2RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9375481-B2 | Drug loaded polymeric nanoparticles and methods of making and using same | BIND THERAPEUTICS, INC. (US) | 2016-06-28 | — | — | US | disclosed |
| US-20140356444-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | BIND THERAPEUTICS, INC. (US) | 2014-12-04 | — | — | US | disclosed |
| US-8663700-B2 | Drug loaded polymeric nanoparticles and methods of making and using same | BIND THERAPEUTICS, INC. (US) | 2014-03-04 | — | — | US | disclosed |
| US-20130302433-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | PFIZER INC. | 2013-11-14 | — | — | US | disclosed |
| US-8206747-B2 | Drug loaded polymeric nanoparticles and methods of making and using same | BIND BIOSCIENCES, INC. (US) | 2012-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140356444-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | LDHA, LDHB, LPXN | FOLH1 177/4885NAALAD2 2442/4885RIMKLA 1489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.