LDHB

L-lactate dehydrogenase B chain · P07195 · LDHB on Sugi Atlas →

14,324 patent compounds predicted against LDHB, 7,535 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL235873 SCHEMBL235873 1.00 14/20
SCHEMBL481774 SCHEMBL481774 0.57 14/20
SCHEMBL481775 SCHEMBL481775 0.57 14/20
SCHEMBL482107 SCHEMBL482107 0.57 14/20
SCHEMBL2622271 SCHEMBL2622271 0.84 13/20
SCHEMBL481889 SCHEMBL481889 0.47 12/20
SCHEMBL426471 SCHEMBL426471 1.00 11/20
SCHEMBL2754182 SCHEMBL2754182 0.71 11/20
SCHEMBL481822 SCHEMBL481822 0.51 10/20
SCHEMBL481823 SCHEMBL481823 0.51 10/20
SCHEMBL233361 SCHEMBL233361 1.00 9/20
SCHEMBL488599 SCHEMBL488599 0.55 9/20
SCHEMBL839613 SCHEMBL839613 0.52 9/20
SCHEMBL913833 SCHEMBL913833 0.50 9/20
SCHEMBL481702 SCHEMBL481702 0.44 9/20
SCHEMBL481744 SCHEMBL481744 0.44 9/20
SCHEMBL257487 SCHEMBL257487 0.42 8/20
SCHEMBL2622272 SCHEMBL2622272 0.54 7/20
Pki-166 Pki-166 (SCHEMBL173524) 0.44 7/20
Pki-166 Pki-166 (SCHEMBL177814) 0.44 7/20

Clinical trials — most relevant to LDHB by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Mitochondrial Redox Modulation in Newly Diagnosed Type 2 Diabetes: A Randomized Controlled Trial Comparing Imeglimin vs. Metformin Monotherapy PHASE4NOT_YET_RECRUITING
Study to Evaluate the Safety of Pembrolizumab in Participants With Unresectable or Metastatic Melanoma or Non-small Cell Lung Cancer in India (MK-3475-593/KEYNOTE-593) PHASE4COMPLETED
Early Lactate-Directed Therapy in the Intensive Care Unit (ICU) PHASE3COMPLETED
First-line Irinotecan, Lederfolin and 5FU (FOLFIRI) and Bevacizumab in Patients With Advanced Colorectal Cancer PHASE2COMPLETED
Study to Evaluate the Efficacy and Safety of REGN3918 in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) PHASE2COMPLETED
Hyperpolarized 13C Pyruvate MRI Scan in Predicting Tumor Aggressiveness in Patients With Renal Tumors PHASE2ACTIVE_NOT_RECRUITING
A Single-arm Phase 2 Prospective Clinical Study of Enatumab in the Treatment of Relapsed/Refractory Warm Antibody Autoimmune Hemolytic Anemia PHASE2NOT_YET_RECRUITING
Acetylcarnitine and Insulin Sensitivity PHASE2COMPLETED
Role of LDH as a Predictor of Treatment Outcomes in Hepatocellular Carcinoma nanUNKNOWN
The Predictive Value of Heart Rate Variability for the Prognosis of Patients With Mild to Moderate Traumatic Brain Injury nanCOMPLETED
Swiss Austrian German Testicular Cancer Cohort Study - SAG TCCS nanRECRUITING
Implication of Long Non-coding RNA CCDC144NL-AS1/Micro RNA-143-3p Axis Expression Level as Novel Signature in Colorectal Cancer nanCOMPLETED
Evaluation of Clinical Characteristics and Outcome of COVID19 Pneumonia in Assiut University Hospital nanUNKNOWN
Evaluation of Lactate Dehydrogenase as Decision Support for Admissions to Neonatal Ward nanCOMPLETED
NLR AND CRP Useful as Cost-Effective Preliminary Prognostic Markers in ST-Elevation Myocardial Infarction nanRECRUITING
Study of CRP, Ferritine and D-Dimer in Covid-19 Patients Admitted To Respiratory ICU in Assuit University Hospitals nanUNKNOWN
COVID-19 Study at the Russian Clinical and Research Center of Gerontology of the Pirogov RNRMU nanCOMPLETED
Efficacy of Navigable Percutaneous Plasma Disc Decompression Device (L'DISQ) in Patients With Severe Lumbar Disc Herniation nanUNKNOWN
The Effectiveness of Surgical Treatment of Patients With Ischemic Cardiomyopathy nanCOMPLETED
Early Goal Directed Therapy Using a Physiological Holistic View. The ANDROMEDA-SHOCK Study nanCOMPLETED
Effects of Krill Oil on Intestinal Integrity Markers in Elite Rowers. nanUNKNOWN
Remote Ischemic Postconditioning in Humans nanCOMPLETED
Artemisinin Resistance In Malaria Treated With IV Artesunate nanWITHDRAWN
Single Effort in Air Temperature of Minus 10°C nanCOMPLETED
Effects of Protein Hydrolysate Supplementation Influencing Strength Recovery and Expression of Muscle Damage Markers Post-exercise nanCOMPLETED
Infrared Low-level Laser Therapy Before Intense Progressive Running Test of High-level Soccer Players nanCOMPLETED
Correlation Between Inferior Vena Cava Collapsibility Index and Serum Lactate in Poly-trauma Patients nanNOT_YET_RECRUITING
Minimally-Invasive Realtime Assessment of Continuous Lactate in Exercise nanUNKNOWN
Evaluation of a PCM Mattress to Treat HIE Infants During Transport nanUNKNOWN
CBC Indices and Serum Lactate in Neonatal Sepsis nanNOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a LDHB binder may also engage these)

ProteinNameSimilarity
Q9XT86 1.000 Q9XT86 →
P16125 1.000 P16125 →
A0A1F3 1.000 A0A1F3 →
Q4R5B6 1.000 Q4R5B6 →
P00337 1.000 P00337 →
A5A6N7 1.000 A5A6N7 →
P00336 1.000 P00336 →
Q9XT87 1.000 Q9XT87 →
Q5E9B1 1.000 Q5E9B1 →
LDHA L-lactate dehydrogenase A chain 1.000 landscape →
P42123 1.000 P42123 →
P00341 1.000 P00341 →
Q9PT42 1.000 Q9PT42 →
Q9PW05 1.000 Q9PW05 →
Q98SL0 1.000 Q98SL0 →
Q9PT43 1.000 Q9PT43 →
Q9W7M6 0.998 Q9W7M6 →
Q1EG91 0.998 Q1EG91 →
P69082 0.998 P69082 →
Q98SK9 0.998 Q98SK9 →
O93542 0.998 O93542 →
O93546 0.997 O93546 →
Q9YGL2 0.997 Q9YGL2 →
Q98SL2 0.997 Q98SL2 →
Q9W7L5 0.997 Q9W7L5 →
P04642 0.997 P04642 →
O93537 0.997 O93537 →
Q98SL1 0.997 Q98SL1 →
P42119 0.996 P42119 →
Q9PW06 0.996 Q9PW06 →