Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.67 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.64 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | PDE5A | O76074 | 6/20 | 0.61 |
| ▸ | KDM1A | O60341 | 1/20 | 0.59 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.56 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
| ▸ | PRKACA | P17612 | 1/20 | 0.56 |
| ▸ | LTK | P29376 | 1/20 | 0.56 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.56 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.56 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10131633 | 0.84 | CSNK2A1 (0.67) | NPY5RCSNK2A1ABCG2MEN1KMT2A | |
| SCHEMBL13702755 | 0.84 | CSNK2A1 (0.65) | NPY5RCSNK2A1ABCG2MEN1KMT2A | |
| SCHEMBL17740777 | 0.84 | ABCG2 (0.57) | CSNK2A1ABCG2MEN1KMT2APDE5A | |
| SCHEMBL19261422 | 0.83 | PDE5A (0.70) | NPY5RCSNK2A1ABCG2MEN1KMT2A | |
| SCHEMBL13903883 | 0.82 | MEN1 (0.69) | NPY5RABCG2MEN1KMT2APDE5A | |
| SCHEMBL1755564 | 0.82 | ALDH1A1 (0.48) | NPY5RCSNK2A1ABCG2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1705655 | 0.80 | ALDH1A1 (0.46) | NPY5RCSNK2A1ABCG2MEN1KMT2A | |
| SCHEMBL2591063 | 0.80 | NPY5R (1.00) | NPY5RABCG2MEN1KMT2APDE5A | |
| SCHEMBL10135169 | 0.79 | CSNK2A1 (0.59) | CSNK2A1ABCG2MEN1KMT2AEGFR | |
| SCHEMBL4972017 | 0.79 | CSNK2A1 (1.00) | CSNK2A1CLK4DAPK3PIM1CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168651-B2 | Protein kinase modulators | CYLENE PHARMACEUTICALS, INC. (US) | 2012-05-01 | — | — | US | disclosed |
| US-8168651-B2 | Protein kinase modulators | CYLENE PHARMACEUTICALS, INC. (US) | 2012-05-01 | — | — | US | disclosed |