Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 10/20 | 1.00 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.64 |
| ▸ | RELA | Q04206 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.64 |
| ▸ | AURKA | O14965 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6039677 | 0.98 | NPY5R (0.96) | NPY5RSLC2A1SMN1; SMN2TAAR1POLB | |
| SCHEMBL8901062 | 0.92 | NPY5R (0.84) | NPY5RSLC2A1SMN1; SMN2TAAR1POLB | |
| SCHEMBL8898077 | 0.92 | NPY5R (0.84) | NPY5RSLC2A1TSHRMAPK1MEN1 | |
| Hydrochloric Acid SCHEMBL8900449 | 0.90 | NPY5R (0.81) | NPY5RSLC2A1SMN1; SMN2TAAR1POLB | |
| Hydrochloric Acid SCHEMBL8900034 | 0.90 | NPY5R (0.81) | NPY5RSLC2A1SMN1; SMN2TAAR1POLB | |
| SCHEMBL8890945 | 0.90 | NPY5R (1.00) | NPY5RSLC2A1SMN1; SMN2HTTTP53 | |
| SCHEMBL8890555 | 0.90 | NPY5R (1.00) | NPY5RSLC2A1TAAR1POLBNPC1 | |
| SCHEMBL8890734 | 0.90 | NPY5R (0.81) | NPY5RSLC2A1SMN1; SMN2TAAR1POLB | |
| Hydrochloric Acid SCHEMBL8898758 | 0.90 | NPY5R (0.81) | NPY5RSLC2A1SMN1; SMN2TAAR1POLB | |
| Hydrochloric Acid SCHEMBL8900357 | 0.89 | NPY5R (0.97) | NPY5RSLC2A1SMN1; SMN2POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3108900-B1 | PROTOTYPE SYSTEMS OF THERANOSTIC BIOMARKERS FOR IN VIVO MOLECULAR MANAGEMENT OF CANCER | EPOS IASIS RES AND DEVELOPMENT LTD (CY) | 2019-04-24 | — | — | EP | claimed |
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |
| EP-2566480-A2 | METHODS AND COMPOSITIONS FOR INHIBITION OF THE TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE | California Institute of Technology (US) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011140527-A2 | METHODS AND COMPOSITIONS FOR INHIBITION OF THE TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE | CALIFORNIA INSTITUTE OF TECHNOLOGY AND THE UNIVERSITY OF KANSAS (US) | 2011-11-10 | — | — | WO | disclosed |