Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 6/20 | 0.39 |
| ▸ | ARG1 | P05089 | 1/20 | 0.38 |
| ▸ | ARG2 | P78540 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 4/20 | 0.38 |
| ▸ | NOS1 | P29475 | 3/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18650351 | 0.82 | SLC1A3 (0.38) | SLC1A3SLC1A2SLC1A1IDO1KIF11 | |
| SCHEMBL1277876 | 0.81 | ALDH1A1 (0.36) | SLC1A3SLC1A2SLC1A1IDO1KIF11 | |
| SCHEMBL18650353 | 0.80 | NOS2 (0.38) | SLC1A3SLC1A2SLC1A1IDO1KIF11 | |
| SCHEMBL14177534 | 0.80 | IDO1 (0.38) | SLC1A3SLC1A2SLC1A1IDO1KIF11 | |
| SCHEMBL9335693 | 0.80 | SLC1A1 (0.41) | SLC1A3SLC1A2SLC1A1KIF11ARG1 | |
| SCHEMBL9335697 | 0.80 | SLC1A1 (0.41) | SLC1A3SLC1A2SLC1A1KIF11ARG1 | |
| SCHEMBL18650328 | 0.79 | SLC7A5 (0.37) | SLC1A3SLC1A2SLC1A1IDO1KIF11 | |
| Hydrochloric Acid SCHEMBL20510440 | 0.79 | IDO1 (0.40) | SLC1A3SLC1A2SLC1A1IDO1KIF11 | |
| Hydrochloric Acid SCHEMBL20510441 | 0.79 | IDO1 (0.40) | SLC1A3SLC1A2SLC1A1IDO1KIF11 | |
| Hydrochloric Acid SCHEMBL20510841 | 0.78 | IDO1 (0.39) | SLC1A3SLC1A2SLC1A1IDO1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2796546-B1 | Incorporation of unnatural amino acids | SCRIPPS RESEARCH INST (US) | 2017-08-09 | — | — | EP | disclosed |
| EP-2796546-A1 | In vivo incorporation of unnatural amino acids | The Scripps Research Institute (US) | 2014-10-29 | — | — | EP | disclosed |
| US-20120202243-A1 | IN Vivo Incorporation of Unnatural Amino Acids | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-08-09 | — | — | US | disclosed |
| US-8173392-B2 | In vivo incorporation of unnatural amino acids | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-05-08 | — | — | US | disclosed |
| US-20120101006-A1 | Methods and Compositions for the Production of Orthogonal tRNA-Aminoacyl tRNA Synthetase Pairs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-04-26 | — | — | US | disclosed |
| US-8012739-B2 | Methods and compositions for the production of orthogonal tRNA-aminoacyl-tRNA synthetase pairs | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-09-06 | — | — | US | disclosed |
| US-20090227002-A1 | Methods and compositions for the production of orthogonal tRNA-aminoacyl tRNA synthetase pairs | THE SCRIPPS RESEARCH INSTITUTE and THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2009-09-10 | — | — | US | disclosed |
| US-20090068717-A1 | In vivo incorporation of unnatural amino acids | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-03-12 | — | — | US | disclosed |
| US-20080227152-A1 | Translation systems with orthogonal aminoacyl tRNA synthetase; membrane proteins | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-09-18 | — | — | US | disclosed |