SCHEMBL10136034

SCHEMBL10136034

CCCCN(CCNC(=O)CCC(=O)O)C(=O)CCC(=O)O

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.47
EPHX2 P34913 3/20 0.42
CASP2 P42575 1/20 0.42
KDM5A P29375 8/20 0.42
KDM4C Q9H3R0 7/20 0.42
FAAH O00519 2/20 0.41
CNR1 P21554 2/20 0.41
CNR2 P34972 2/20 0.41
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.40
SLC6A5 Q9Y345 1/20 0.40
PHF8 Q9UPP1 3/20 0.40
KDM4A O75164 1/20 0.40
NAAA Q02083 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10136011 0.88 DNM1 (0.47) DNM1CASP2FAAHCNR1KMT2A
SCHEMBL30890794 0.85 DNM1 (0.56) DNM1EPHX2CASP2FAAHKDM4A
SCHEMBL10787440 0.85 AKR1B1 (0.50) KDM5AKDM4CMEN1KMT2A
SCHEMBL7897141 0.84 CASP2 (0.62) DNM1EPHX2CASP2FAAHSLC6A5
SCHEMBL25353415 0.83 DNM1 (0.62) DNM1EPHX2FAAHCNR1CNR2
SCHEMBL6860236 0.83 DNM1 (0.50) DNM1EPHX2CASP2FAAHCNR1
SCHEMBL585370 0.83 CASP2 (0.56) DNM1EPHX2CASP2FAAHCNR1
SCHEMBL27665153 0.82 KDM5A (0.53) DNM1EPHX2CASP2KDM5AKDM4C
Hydrochloric Acid SCHEMBL27665152 0.81 KDM5A (0.51) DNM1EPHX2CASP2KDM5AKDM4C
SCHEMBL26037662 0.81 CASP2 (0.58) DNM1EPHX2CASP2FAAHCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1895979-B1 COSMETICS COMPRISING A MODIFIED ORGANOPOLYSILOXANE DOW CORNING TORAY CO LTD (JP) 2014-03-12 EP disclosed
US-8147854-B2 Cosmetics comprising a modified organopolysiloxane DOW CORNING TORAY COMPANY, LTD. (JP) 2012-04-03 US disclosed
EP-1907068-B1 GELLING AGENT COMPRISING A MODIFIED ORGANOPOLYSILOXANE DOW CORNING TORAY CO LTD (JP) 2011-09-07 EP disclosed
US-8013094-B2 Gelling agents and gelatinous compositions DOW CORNING TORAY COMPANY, LTD. (JP) 2011-09-06 US disclosed
US-20100029862-A1 Gelling Agents And Gelatinous Compositions DOW CORNING TORAY COMPANY, LTD. (JP) 2010-02-04 US disclosed
US-20100028391-A1 Cosmetics Comprising A Modified Organopolysiloxane DOW CORNING TORAY COMPANY, LTD. (JP) 2010-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100028391-A1 Cosmetics Comprising A Modified Organopolysiloxane H1-0, H1-2, CHRM1 DNM1 4338/4885EPHX2 1691/4885CASP2 4144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.