SCHEMBL10136602

SCHEMBL10136602

CNC(=O)c1cc(C#N)cc(C)c1NC(=O)c1cc(C(O)Cn2nnc(C(F)(F)F)n2)nn1-c1ncccc1Cl

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 9/20 0.34
SLC2A3 P11169 9/20 0.34
SLC2A4 P14672 9/20 0.34
SLC2A2 P11168 2/20 0.34
ALDH1A1 P00352 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29454974 0.89 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2ALDH1A1
SCHEMBL798149 0.89 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2ALDH1A1
SCHEMBL29454972 0.89 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2ALDH1A1
SCHEMBL29454976 0.89 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2ALDH1A1
SCHEMBL13085527 0.89 SLC2A1 (0.33) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL10118295 0.88 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2ALDH1A1
SCHEMBL2623667 0.84 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2ALDH1A1
SCHEMBL15963579 0.84 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2ALDH1A1
SCHEMBL15246061 0.84 LIMK1 (0.37) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL13085303 0.83 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2582688-B1 ANTHRANILIC ACID DIAMIDE DERIVATIVES BAYER IP GMBH (DE) 2015-10-07 EP disclosed
US-8791139-B2 Anthranilic diamide derivatives BAYER CROPSCIENCE AG (DE) 2014-07-29 US disclosed
US-20120015980-A1 ANTHRANILIC DIAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2012-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120015980-A1 ANTHRANILIC DIAMIDE DERIVATIVES DDT, QDPR, ANTXR2 SLC2A1 3127/4885SLC2A3 3314/4885SLC2A4 3392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.