SCHEMBL2623667

SCHEMBL2623667

CNC(=O)c1cc(C#N)cc(C)c1NC(=O)c1cc(Cn2nnc(C(C)(F)F)n2)nn1-c1ncccc1Cl

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 11/20 0.34
SLC2A3 P11169 11/20 0.34
SLC2A4 P14672 11/20 0.34
SLC2A2 P11168 4/20 0.34
DHODH Q02127 2/20 0.32
SLC16A3 O15427 2/20 0.32
SLC16A1 P53985 2/20 0.32
MCTS1 Q9ULC4 1/20 0.32
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CACNA1H O95180 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29454972 0.95 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL29454976 0.95 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL29454974 0.95 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL798149 0.95 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL11928145 0.94 SLC2A1 (0.32) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL10083626 0.94 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL13085303 0.94 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL11928142 0.93 SLC2A1 (0.33) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL15963579 0.91 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL798276 0.90 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9056861-B2 Process for preparing tetrazole-substituted anthranilamide derivatives and novel crystal polymorphs of these derivatives BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-06-16 US disclosed
US-8969572-B2 Process for preparing tetrazole-substituted anthranilamide derivatives and novel crystal polymorphs of these derivatives BAYER CROPSCIENCE AG (DE) 2015-03-03 US disclosed
US-20150025116-A1 PROCESS FOR PREPARING TETRAZOLE-SUBSTITUTED ANTHRANILAMIDE DERIVATIVES AND NOVEL CRYSTAL POLYMORPHS OF THESE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2015-01-22 US disclosed
US-20120101133-A1 PROCESS FOR PREPARING TETRAZOLE-SUBSTITUTED ANTHRANILAMIDE DERIVATIVES AND NOVEL CRYSTAL POLYMORPHS OF THESE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2012-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150025116-A1 PROCESS FOR PREPARING TETRAZOLE-SUBSTITUTED ANTHRANILAMIDE DERIVATIVES AND NOVEL CRYSTAL POLYMORPHS OF THESE DERIVATIVES CYP4F3, CYP4F12, CYP3A5 SLC2A1 4160/4885SLC2A3 3615/4885SLC2A4 3964/4885
US-20120101133-A1 PROCESS FOR PREPARING TETRAZOLE-SUBSTITUTED ANTHRANILAMIDE DERIVATIVES AND NOVEL CRYSTAL POLYMORPHS OF THESE DERIVATIVES CYP4F3, CYP4F12, CYP3A5 SLC2A1 4160/4885SLC2A3 3615/4885SLC2A4 3964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.