SCHEMBL10136741

SCHEMBL10136741

COC(=O)C#CC(C)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25706 0.87 ALDH1A1 (0.44)
SCHEMBL11356961 0.78 ALDH1A1 (0.38)
SCHEMBL609904 0.77
SCHEMBL10962562 0.77 ALDH1A1 (0.35)
SCHEMBL1899467 0.77
SCHEMBL11351014 0.77 ALDH1A1 (0.35)
SCHEMBL2939248 0.75 ALDH1A1 (0.39)
SCHEMBL12174598 0.74 ALDH1A1 (0.33)
SCHEMBL27905777 0.74
SCHEMBL7146408 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230140413-A1 Compounds and Methods for Treating, Detecting, and Identifying Compounds to Treat Apicomplexan Parasitic Diseases THE UNIVERSITY OF CHICAGO 2023-05-04 US disclosed
US-20230126055-A1 SELECTIVE BLOCKING OF METAL SURFACES USING BIFUNCTIONAL SELF-ASSEMBLED MONOLAYERS APPLIED MATERIALS, INC. (US) 2023-04-27 US disclosed
EP-1996539-B1 METHOD AND APPARATUS FOR CONDUCTING MICROWAVE ASSISTED ORGANIC REACTIONS WITH GAS-PHASE REACTANTS CEM CORP (US) 2016-06-29 EP disclosed
US-9115869-B2 Wavelength converting element KONINKLIJKE PHILIPS N.V. (NL) 2015-08-25 US disclosed
US-20150064111-A1 NOVEL TARGETING AGENTS FOR DIAGNOSTIC AND THERAPEUTIC INDICATIONS APOSENSE LTD. (IL) 2015-03-05 US disclosed
US-20140153247-A1 WAVELENGTH CONVERTING ELEMENT KONINKLIJKE PHILIPS N.V. (NL) 2014-06-05 US disclosed
US-8334317-B2 Calcium receptor modulating agents AMGEN INC. (US) 2012-12-18 US disclosed
US-20120269769-A1 Hepatitis C Inhibitor Compounds BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-10-25 US disclosed
US-20120034187-A1 Hepatitis C Inhibitor Compounds BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-02-09 US disclosed
US-8067438-B2 Hepatitis C inhibitor compounds BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-11-29 US disclosed
US-20110177030-A1 Hepatitis C Inhibitor Compounds BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-07-21 US disclosed
US-20110178133-A1 CALCIUM RECEPTOR MODULATING AGENTS AMGEN INC. 2011-07-21 US disclosed
US-7939667-B2 Hepatitis C inhibitor compounds BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-05-10 US disclosed
US-20100028300-A1 MACROCYCLIC PEPTIDES ACTIVE AGAINST THE HEPATITIS C VIRUS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-02-04 US disclosed
US-7304092-B1 Compounds and methods for treating tumors, cancer and hyperproliferative diseases YALE UNIVERSITY (US) 2007-12-04 US disclosed
WO-2007103501-A2 METHOD AND APPARATUS FOR CONDUCTING MICROWAVE ASSISTED ORGANIC REACTIONS WITH GAS-PHASE REACTANTS CEM, CORPORATION (US) 2007-09-13 WO disclosed