⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627877 | 1.00 | — | — | |
| SCHEMBL26771037 | 0.64 | ESR1 (0.30) | — | |
| SCHEMBL45848 | 0.61 | TP53 (0.33) | — | |
| SCHEMBL1902706 | 0.58 | — | — | |
| SCHEMBL10074739 | 0.58 | — | — | |
| SCHEMBL851507 | 0.58 | — | — | |
| SCHEMBL45869 | 0.57 | KCNH2 (0.52) | — | |
| SCHEMBL12151300 | 0.56 | — | — | |
| SCHEMBL11564452 | 0.56 | KCNH2 (0.50) | — | |
| SCHEMBL830188 | 0.55 | NOS3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116924976-A | Diaryl heterocyclic amine compound, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2023-10-24 | — | — | CN | claimed |
| EP-4698524-A1 | TRIARYL AGONISTS OF ALPHA-2 ADRENERGIC RECEPTORS | Alceptor Therapeutics, Inc. (US) | 2026-02-25 | — | — | EP | disclosed |
| US-20250382304-A1 | HETEROAROMATIC MACROCYCLIC ETHER CHEMOTHERAPEUTIC AGENTS | NUVALENT INC (US) | 2025-12-18 | — | — | US | disclosed |
| US-12202826-B2 | N-pyridinyl acetamide derivatives as inhibitors of the Wnt signaling pathway | REDX PHARMA PLC (GB) | 2025-01-21 | — | — | US | disclosed |
| CN-118903118-A | Use of 3-substituted naphtho [2,3-b ] isoxazole-4, 9-dione derivatives for anti-psoriasis | 中南大学 | 2024-11-08 | — | — | CN | disclosed |
| WO-2024220941-A1 | TRIARYL AGONISTS OF ALPHA-2 ADRENERGIC RECEPTORS | ALCEPTOR THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |
| WO-2024141757-A1 | LSD1 MODULATORS | EXSCIENTIA AI LIMITED (GB) | 2024-07-04 | — | — | WO | disclosed |
| US-20230365549-A1 | N-PYRIDINYL ACETAMIDE DERIVATIVES AS INHIBITORS OF THE WNT SIGNALING PATHWAY | REDX PHARMA PLC (GB) | 2023-11-16 | — | — | US | disclosed |
| CN-116924976-A | Diaryl heterocyclic amine compound, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2023-10-24 | — | — | CN | disclosed |
| US-11786528-B2 | Pyrazolopyrimidine compounds as adenosine receptor antagonists | EXSCIENTIA LTD. (GB) | 2023-10-17 | — | — | US | disclosed |
| US-20070004675-A1 | Inhibitors of VEGF receptor and HGF receptor signaling | METHYLGENE, INC. | 2007-01-04 | — | — | US | disclosed |
| US-20060025415-A1 | Compositions useful as inhibitors of voltage-gated sodium channels | VERTEX PHARMACEUTICALS INCORPORATED | 2006-02-02 | — | — | US | disclosed |
| US-6576765-B2 | Process for preparing amic acid esters | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-06-10 | — | — | US | disclosed |
| EP-1289970-A1 | 3-ARYLISOTHIAZOLES AND THEIR USE AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-12 | — | — | EP | disclosed |
| US-20030032667-A1 | PROCESS FOR PREPARING AMIC ACID ESTERS | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-02-13 | — | — | US | disclosed |
| EP-1182199-A1 | PROCESS FOR PREPARING AMIC ACID ESTERS | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2002-02-27 | — | — | EP | disclosed |
| WO-2001087863-A1 | 3-ARYLISOTHIAZOLES AND THEIR USE AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-22 | — | — | WO | disclosed |
| WO-1994021617-A1 | A PROCESS FOR PREPARING HALOGENATED ISOTHIAZOLES | DOWELANCO (US) | 1994-09-29 | — | — | WO | disclosed |
| EP-0424444-A1 | COSMETIC COMPOSITIONS BASED ON CHROMONE-CARBOXYLATE. | TRANSPHYTO SA (FR) | 1991-05-02 | — | — | EP | disclosed |
| WO-1990000388-A1 | COSMETIC COMPOSITIONS BASED ON CHROMONE-CARBOXYLATE | TRANSPHYTO S.A. (FR) | 1990-01-25 | — | — | WO | disclosed |