SCHEMBL1013825

SCHEMBL1013825

CCOC(=O)C(=O)NCc1cccc(Br)c1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
HPGD P15428 1/20 0.52
CYP19A1 P11511 1/20 0.49
KMT2A Q03164 1/20 0.47
NPC1 O15118 1/20 0.47
GPR35 Q9HC97 2/20 0.47
ALOX5 P09917 1/20 0.46
SLC26A6 Q9BXS9 1/20 0.46
MTOR P42345 1/20 0.45
MAPT P10636 2/20 0.45
THRB P10828 1/20 0.44
CHRM4 P08173 1/20 0.44
KDM4E B2RXH2 1/20 0.44
MAPK1 P28482 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12493057 0.90 GPR35 (0.50) HPGDKMT2AGPR35MAPT
SCHEMBL10242983 0.85 TSHR (0.58) LMNAHPGDKMT2ANPC1ALOX5
SCHEMBL25780266 0.85 GPR35 (0.55) LMNACYP19A1KMT2ANPC1GPR35
SCHEMBL17235939 0.83 GPR35 (0.44) KMT2AGPR35MAPTTHRBKDM4E
SCHEMBL25780269 0.83 EPHX2 (0.49) SLC26A6MAPTKDM4EMAPK1
SCHEMBL15682692 0.83 RXFP1 (0.53) KMT2ANPC1GPR35MAPT
SCHEMBL15682691 0.82 MEN1 (0.53) LMNAKMT2AGPR35MAPTKDM4E
SCHEMBL19500086 0.82 LMNA (0.48) LMNAHPGDKMT2ANPC1ALOX5
SCHEMBL11169677 0.82 PPID (0.60) LMNAKMT2AMAPT
SCHEMBL25780180 0.81 MAPT (0.53) LMNAHPGDKMT2ANPC1GPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023118434-A1 PESTICIDALLY ACTIVE AMIDE COMPOUNDS GLOBACHEM NV (BE) 2023-06-29 WO disclosed
EP-2272822-A1 INHIBITOR OF PLASMINOGEN ACTIVATOR INHIBITOR-1 Renascience CO., LTD. (JP) 2011-01-12 EP disclosed