Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16215956 | 0.81 | EPHX2 (0.48) | EPHX2EPHX1 | |
| SCHEMBL1406566 | 0.79 | EPHX1 (0.50) | EPHX2EPHX1SIGMAR1 | |
| SCHEMBL13195554 | 0.79 | EPHX1 (0.50) | EPHX2EPHX1SIGMAR1 | |
| SCHEMBL1406564 | 0.79 | EPHX1 (0.50) | EPHX2EPHX1SIGMAR1 | |
| SCHEMBL15436731 | 0.79 | EPHX2 (0.50) | EPHX2EPHX1 | |
| SCHEMBL13195984 | 0.79 | EPHX2 (0.50) | EPHX2EPHX1 | |
| Hydrochloric Acid SCHEMBL1407060 | 0.78 | EPHX1 (0.49) | EPHX2EPHX1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL1406838 | 0.78 | EPHX1 (0.49) | EPHX2EPHX1SIGMAR1 | |
| SCHEMBL2638872 | 0.77 | EPHX2 (0.57) | EPHX2EPHX1SIGMAR1 | |
| SCHEMBL13195994 | 0.77 | EPHX2 (0.44) | EPHX2EPHX1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012059932-A1 | 2, 4 -DIAMINOPYRIMIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2012-05-10 | — | — | WO | disclosed |