Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13195984 | 1.00 | EPHX2 (0.50) | EPHX2ALDH1A1KMT2ASMN1; SMN2HDAC3 | |
| SCHEMBL8403724 | 0.84 | EPHX2 (0.66) | EPHX2ALDH1A1KMT2ASMN1; SMN2HDAC3 | |
| SCHEMBL1406566 | 0.81 | EPHX1 (0.50) | EPHX2KMT2ASMN1; SMN2EPHX1 | |
| SCHEMBL13195554 | 0.81 | EPHX1 (0.50) | EPHX2KMT2ASMN1; SMN2EPHX1 | |
| SCHEMBL1406564 | 0.81 | EPHX1 (0.50) | EPHX2KMT2ASMN1; SMN2EPHX1 | |
| SCHEMBL19271804 | 0.80 | EPHX2 (0.55) | EPHX2ALDH1A1KMT2ASMN1; SMN2HDAC3 | |
| Hydrochloric Acid SCHEMBL1407060 | 0.80 | EPHX1 (0.49) | EPHX2KMT2ASMN1; SMN2EPHX1 | |
| Hydrochloric Acid SCHEMBL1406838 | 0.80 | EPHX1 (0.49) | EPHX2KMT2ASMN1; SMN2EPHX1 | |
| SCHEMBL16215956 | 0.80 | EPHX2 (0.48) | EPHX2KMT2ASMN1; SMN2EPHX1 | |
| SCHEMBL10138566 | 0.79 | EPHX2 (0.44) | EPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687515-A1 | METHOD FOR PRODUCING PYRAZOLECARBOXYLIC ACID DERIVATIVE | Shionogi & Co., Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |
| US-20140012013-A1 | METHOD FOR PRODUCING PYRAZOLE CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2014-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140012013-A1 | METHOD FOR PRODUCING PYRAZOLE CARBOXYLIC ACID DERIVATIVE | HSD11B1, HSD11B2, HSD17B1 | EPHX2 790/4885ALDH1A1 115/4885KMT2A 3174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.