Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365880 | 0.84 | MAPT (0.60) | HCAR3MAPTMAPK1ALDH1A1TDP1 | |
| Phosphonic Acid SCHEMBL27291442 | 0.77 | MAPT (0.56) | HCAR3MAPTMAPK1ALDH1A1TDP1 | |
| Alcohol SCHEMBL5697786 | 0.77 | MAPT (0.56) | HCAR3MAPTMAPK1ALDH1A1TDP1 | |
| SCHEMBL430629 | 0.77 | MAPT (0.59) | HCAR3MAPTMAPK1ALDH1A1TDP1 | |
| SCHEMBL7357317 | 0.76 | MAPT (0.55) | HCAR3MAPTMAPK1ALDH1A1TDP1 | |
| SCHEMBL5350139 | 0.75 | MEN1 (0.52) | HCAR3MAPTMAPK1ALDH1A1TDP1 | |
| SCHEMBL6522547 | 0.75 | HCAR3 (0.57) | HCAR3MAPTMAPK1ALDH1A1TDP1 | |
| SCHEMBL10534498 | 0.74 | HTT (0.71) | HCAR3MAPTMAPK1ALDH1A1TDP1 | |
| SCHEMBL7258796 | 0.74 | TSHR (0.62) | HCAR3MAPTMAPK1ALDH1A1TDP1 | |
| Aniline SCHEMBL27777480 | 0.74 | MAPT (0.61) | HCAR3MAPTMAPK1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012059932-A1 | 2, 4 -DIAMINOPYRIMIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2012-05-10 | — | — | WO | disclosed |