SCHEMBL1014010

SCHEMBL1014010

C[C@@H](O)[C@@H](O)[C@H](O)[C@@H](C)O

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
LMNA P02545 1/20 0.50
TSHR P16473 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
MAPT P10636 1/20 0.35
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL284632 1.00 ALDH1A1 (0.50) ALDH1A1LMNATSHRTDP1MAPT
SCHEMBL5407366 1.00 ALDH1A1 (0.50) ALDH1A1LMNATSHRTDP1MAPT
SCHEMBL14129694 1.00 ALDH1A1 (0.50) ALDH1A1LMNATSHRTDP1MAPT
SCHEMBL13969438 1.00 ALDH1A1 (0.50) ALDH1A1LMNATSHRTDP1MAPT
SCHEMBL30392575 1.00 ALDH1A1 (0.50) ALDH1A1LMNATSHRTDP1MAPT
SCHEMBL6702143 1.00 ALDH1A1 (0.50) ALDH1A1LMNATSHRTDP1MAPT
SCHEMBL14754592 1.00 ALDH1A1 (0.50) ALDH1A1LMNATSHRTDP1MAPT
SCHEMBL19171465 1.00 ALDH1A1 (0.50) ALDH1A1LMNATSHRTDP1MAPT
SCHEMBL12807993 0.95 ALDH1A1 (0.46) ALDH1A1LMNATSHRTDP1MAPT
SCHEMBL10070710 0.95 ALDH1A1 (0.46) ALDH1A1LMNATSHRTDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1464322-B2 Use of compositions containing a chosen fluorescent dye and a chosen amphoteric or nonionic surfactant for dyeing human kerateous fibres with a bleaching effect OREAL (FR) 2022-06-01 EP disclosed
CN-107698748-B Dynamic polymer of hybrid cross-linked network and application thereof 翁秋梅 2020-03-10 CN disclosed
EP-1464326-B9 Hair colouring composition containing a fluorescent dye and an associative polymer OREAL (FR) 2018-05-16 EP disclosed
EP-1464326-B1 Hair colouring composition containing a fluorescent dye and an associative polymer L'ORÉAL (FR) 2017-10-25 EP disclosed
EP-1464322-B1 Use of compositions containing a chosen fluorescent dye and a chosen amphoteric or nonionic surfactant for dyeing human kerateous fibres with a bleaching effect OREAL (FR) 2013-06-05 EP disclosed
EP-2018848-B1 Hair composition comprising at least one fluorescent dye and at least one alkali hydroxide agent and method of simultaneous styling, dyeing and/or lightening. OREAL (FR) 2013-01-09 EP disclosed
EP-1464320-B1 Brightening composition comprising a fluorescent dye and a non-associative polymer thickener for human keratinaceous matter OREAL (FR) 2011-01-05 EP disclosed
US-7736631-B2 Cosmetic dye composition with a lightening effect for human keratin materials, comprising at least one fluorescent dye and at least one aminosilicone, and process of dyeing L'OREAL S.A. (FR) 2010-06-15 US disclosed
US-20090288674-A1 COSMETIC DYE COMPOSITION WITH A LIGHTENING EFFECT FOR HUMAN KERATIN MATERIALS, COMPRISING AT LEAST ONE FLUORESCENT DYE AND AT LEAST ONE AMINOSILICONE, AND PROCESS OF DYEING L'OREAL S.A. 2009-11-26 US disclosed
EP-2018848-A2 Hair composition comprising at least one fluorescent dye and at least one alkali hydroxide agent and method of simultaneous styling, dyeing and/or lightening. L'Oreal (FR) 2009-01-28 EP disclosed
EP-1464328-A1 Composition for dyeing human keratinic fibres comprising a fluorescent colouring agent and an insoluble conditioning agent, process and use. L'OREAL (FR) 2004-10-06 EP disclosed
EP-1464324-A1 Dyeing composition for human keratinous material comprising a fluorescent colouring agent and an insoluble polyorganosiloxane conditioning polymer, method and use L'OREAL (FR) 2004-10-06 EP disclosed
EP-1464327-A1 Composition for dyeing human keratinous fibres comprising a fluorescent dyeing agent and a polyol, method and use L'OREAL (FR) 2004-10-06 EP disclosed
EP-1464326-A1 Hair colouring composition containing a fluorescent dye and an associative polymer L'OREAL (FR) 2004-10-06 EP disclosed
EP-1464321-A1 Dyeing composition for keratineous materials comprising a fluorescent dye and an aminated silicone, process and use L'OREAL (FR) 2004-10-06 EP disclosed
EP-1175385-A1 D-MANNITOL DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS Pharmacor Inc. (CA) 2002-01-30 EP disclosed
WO-2000066524-A1 D-MANNITOL DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS PHARMACOR INC. (CA) 2000-11-09 WO disclosed
EP-0729648-A4 STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS UNISEARCH LTD (AU) 1997-01-02 EP disclosed
EP-0729648-A1 STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS UNISEARCH LIMITED (AU) 1996-09-04 EP disclosed
WO-1995012219-A1 STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS UNISEARCH LIMITED (AU) 1995-05-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090288674-A1 COSMETIC DYE COMPOSITION WITH A LIGHTENING EFFECT FOR HUMAN KERATIN MATERIALS, COMPRISING AT LEAST ONE FLUORESCENT DYE AND AT LEAST ONE AMINOSILICONE, AND PROCESS OF DYEING KRT18, MARK1, CUTA ALDH1A1 1284/4885LMNA 396/4885TSHR 3824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.