Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10729588 | 0.87 | IDO1 (0.56) | IDO1ALDH1A1L3MBTL1PYCR1FKBP1A | |
| SCHEMBL8036454 | 0.83 | IDO1 (0.48) | IDO1ALDH1A1L3MBTL1PYCR1FKBP1A | |
| SCHEMBL282563 | 0.82 | IDO1 (0.52) | IDO1ALDH1A1L3MBTL1PYCR1RAB9A | |
| SCHEMBL172620 | 0.82 | IDO1 (0.52) | IDO1L3MBTL1PYCR1RAB9ATYR | |
| SCHEMBL597719 | 0.80 | IDO1 (0.50) | IDO1ALDH1A1L3MBTL1PYCR1FKBP1A | |
| SCHEMBL18463151 | 0.78 | IDO1 (0.48) | IDO1ALDH1A1L3MBTL1PYCR1FKBP1A | |
| SCHEMBL1610104 | 0.78 | IDO1 (0.48) | IDO1ALDH1A1L3MBTL1PYCR1FKBP1A | |
| SCHEMBL7461724 | 0.78 | IDO1 (0.48) | IDO1ALDH1A1L3MBTL1PYCR1FKBP1A | |
| SCHEMBL717640 | 0.78 | TAAR1 (0.56) | IDO1ALDH1A1L3MBTL1MAOBKMT2A | |
| SCHEMBL6548229 | 0.78 | ALDH1A1 (0.57) | IDO1ALDH1A1L3MBTL1RAB9AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021704-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2012-02-16 | — | — | WO | disclosed |
| WO-2011091417-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2011-07-28 | — | — | WO | disclosed |
| WO-2011081918-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC (US) | 2011-07-07 | — | — | WO | disclosed |
| WO-2011031934-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2011-03-17 | — | — | WO | disclosed |