Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24246324 | 0.86 | IDO1 (0.45) | IDO1DHFRL3MBTL1ALDH1A1FKBP1A | |
| SCHEMBL23917953 | 0.85 | MAPT (0.51) | IDO1ALDH1A1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL10729588 | 0.85 | IDO1 (0.56) | IDO1DHFRL3MBTL1ALDH1A1FKBP1A | |
| SCHEMBL18837508 | 0.85 | IDO1 (0.44) | IDO1DHFRL3MBTL1ALDH1A1FKBP1A | |
| SCHEMBL18911133 | 0.82 | LMNA (0.40) | L3MBTL1ALDH1A1LMNA | |
| SCHEMBL2973480 | 0.80 | IDO1 (0.52) | IDO1L3MBTL1PYCR1RAB9ATYR | |
| SCHEMBL9344527 | 0.80 | GFER (0.32) | — | |
| SCHEMBL332100 | 0.79 | GFER (0.42) | IDO1L3MBTL1ALDH1A1MAOB | |
| SCHEMBL597719 | 0.78 | IDO1 (0.50) | IDO1L3MBTL1ALDH1A1FKBP1APYCR1 | |
| SCHEMBL10140562 | 0.78 | IDO1 (0.50) | IDO1DHFRL3MBTL1ALDH1A1FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018135918-A1 | PHARMACEUTICAL COMPOSITION COMPRISING COMPOUND HAVING BLT INHIBITING ACTIVITY AS EFFECTIVE INGREDIENT FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASE | 동국대학교 산학협력단 | 2018-07-26 | — | — | WO | disclosed |
| WO-2017018750-A1 | NOVEL COMPOUND HAVING BLT INHIBITORY ACTIVITY AND COMPOSITION, FOR PREVENTING OR TREATING INFLAMMATORY DISEASES, COMPRISING SAME AS ACTIVE INGREDIENT | 동국대학교 산학협력단 | 2017-02-02 | — | — | WO | disclosed |