Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.63 |
| ▸ | CTSL | P07711 | 1/20 | 0.63 |
| ▸ | CTSB | P07858 | 1/20 | 0.63 |
| ▸ | ELANE | P08246 | 1/20 | 0.63 |
| ▸ | CMA1 | P23946 | 1/20 | 0.63 |
| ▸ | CTSS | P25774 | 1/20 | 0.63 |
| ▸ | CTSK | P43235 | 1/20 | 0.63 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.63 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14451276 | 1.00 | CTSV (0.63) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL13689666 | 1.00 | CTSV (0.63) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL13689670 | 0.98 | CTSV (0.60) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL10226927 | 0.98 | CTSV (0.60) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL14451277 | 0.98 | CTSV (0.60) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL13688788 | 0.93 | CTSS (0.64) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL8355281 | 0.93 | CTSS (0.64) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL10226899 | 0.93 | CTSS (0.64) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL8256281 | 0.93 | CTSS (0.64) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL8354732 | 0.93 | CTSS (0.64) | CTSVCTSLCTSBELANECMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43298-E1 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2012-04-03 | — | — | US | disclosed |
| US-RE43298-E1 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2012-04-03 | — | — | US | disclosed |