Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13154983 | 0.86 | KMT2A (0.45) | NPSR1LMNANPC1ALDH1A1MAPT | |
| SCHEMBL890187 | 0.86 | KMT2A (0.45) | NPSR1LMNANPC1ALDH1A1MAPT | |
| SCHEMBL14757730 | 0.86 | KMT2A (0.45) | NPSR1LMNANPC1ALDH1A1MAPT | |
| SCHEMBL28525767 | 0.83 | RIPK1 (0.46) | NPSR1LMNANPC1ALDH1A1MAPT | |
| SCHEMBL19174905 | 0.83 | RIPK1 (0.46) | NPSR1LMNANPC1ALDH1A1MAPT | |
| SCHEMBL30879793 | 0.79 | TSHR (0.42) | NPSR1LMNANPC1ALDH1A1TSHR | |
| SCHEMBL30679850 | 0.79 | ALOX5AP (0.45) | NPSR1LMNANPC1ALDH1A1MAPT | |
| SCHEMBL25594973 | 0.77 | LMNA (0.48) | NPSR1LMNANPC1ALDH1A1MAPT | |
| SCHEMBL31226469 | 0.76 | ALOX5AP (0.45) | NPSR1LMNANPC1ALDH1A1MAPT | |
| SCHEMBL31226409 | 0.76 | ALOX5AP (0.45) | NPSR1LMNANPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021704-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2012-02-16 | — | — | WO | disclosed |
| WO-2011127350-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2011-10-13 | — | — | WO | disclosed |
| WO-2011091417-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2011-07-28 | — | — | WO | disclosed |
| WO-2011031904-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC (US) | 2011-03-17 | — | — | WO | disclosed |
| WO-2011031934-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2011-03-17 | — | — | WO | disclosed |