Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10119365 | 0.89 | SPHK1 (0.44) | USP2SPHK1HTTSPHK2PRKD3 | |
| SCHEMBL31086433 | 0.89 | SPHK1 (0.44) | USP2SPHK1HTTSPHK2PRKD3 | |
| SCHEMBL7149639 | 0.87 | ALDH1A1 (0.41) | ALDH1A1HSD17B10 | |
| SCHEMBL11858528 | 0.87 | SPHK1 (0.42) | USP2SPHK1HTTSPHK2PRKD3 | |
| SCHEMBL10151453 | 0.85 | USP2 (0.57) | USP2SPHK1HTTPRKD3PRKCG | |
| SCHEMBL10151448 | 0.85 | USP2 (0.57) | USP2SPHK1HTTPRKD3PRKCG | |
| SCHEMBL4489928 | 0.85 | USP2 (0.57) | USP2SPHK1HTTPRKD3PRKCG | |
| SCHEMBL3794737 | 0.85 | USP2 (0.57) | USP2SPHK1HTTPRKD3PRKCG | |
| SCHEMBL4483278 | 0.85 | USP2 (0.57) | USP2SPHK1HTTPRKD3PRKCG | |
| SCHEMBL10151451 | 0.85 | USP2 (0.57) | USP2SPHK1HTTPRKD3PRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9730976-B2 | Homo- and heterodimeric SMAC mimetic compounds as apoptosis inducers | BIONTECH AG (DE) | 2017-08-15 | — | — | US | disclosed |
| US-20160317605-A1 | New Homo- and Heterodimeric SMAC Mimetic Compounds as Apoptosis Inducers | BIONTECH AG (DE) | 2016-11-03 | — | — | US | disclosed |
| US-9321808-B2 | Homo- and heterodimeric SMAC mimetic compounds as apoptosis inducers | BIONTECH AG (DE) | 2016-04-26 | — | — | US | disclosed |
| US-20150119342-A1 | New Homo- and Heterodimeric SMAC Mimetic Compounds as Apoptosis Inducers | UNIVERSITA' DEGLI STUDI DI MILANO (IT) | 2015-04-30 | — | — | US | disclosed |
| US-20120039848-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2012-02-16 | — | — | US | disclosed |
| US-20110250172-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160317605-A1 | New Homo- and Heterodimeric SMAC Mimetic Compounds as Apoptosis Inducers | BID, BIRC2, API5 | USP2 1391/4885SPHK1 3428/4885HTT 1507/4885 |
| US-20110250172-A1 | HEPATITIS C VIRUS INHIBITORS | HAVCR2, SLC10A1, EIF2AK2 | USP2 2741/4885SPHK1 2196/4885HTT 4444/4885 |
| US-20120039848-A1 | HEPATITIS C VIRUS INHIBITORS | HAVCR2, SLC10A1, EIF2AK2 | USP2 2741/4885SPHK1 2196/4885HTT 4444/4885 |
| US-20150119342-A1 | New Homo- and Heterodimeric SMAC Mimetic Compounds as Apoptosis Inducers | BID, BIRC2, API5 | USP2 1391/4885SPHK1 3428/4885HTT 1507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.