SCHEMBL7149639

SCHEMBL7149639

CCOCCOCC(C)C

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
HSD17B10 Q99714 1/20 0.40
TSHR P16473 1/20 0.39
THRB P10828 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12754639 0.97 ALDH1A1 (0.39) ALDH1A1HSD17B10TSHRTHRBTDP1
SCHEMBL7146848 0.97 ALDH1A1 (0.39) ALDH1A1HSD17B10TSHRTHRBTDP1
SCHEMBL723497 0.87 HSD17B10 (0.41) ALDH1A1HSD17B10TSHRTDP1
SCHEMBL10141251 0.87 USP2 (0.42) ALDH1A1HSD17B10
SCHEMBL43710 0.84
SCHEMBL4373347 0.84 HSD17B10 (0.39) ALDH1A1HSD17B10TDP1
SCHEMBL17914307 0.84 HSD17B10 (0.39) ALDH1A1HSD17B10TDP1
SCHEMBL725089 0.84 HSD17B10 (0.39) ALDH1A1HSD17B10TDP1
SCHEMBL8651797 0.84 HSD17B10 (0.39) ALDH1A1HSD17B10TDP1
SCHEMBL17914309 0.84 HSD17B10 (0.39) ALDH1A1HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101724276-B Lignin modified asphalt composition with steady heat storage and preparation method thereof SINOPEC CORP. (CN) 2011-11-30 CN claimed
CN-101210059-B Multipolymer resin water dispersoid containing fluorine and silicon BEIJING UNIVERSITY OF AVIAT AND SPACEFLIGHT 2011-06-15 CN claimed
CN-101654496-B Epoxy resin emulsifying agent and preparation method thereof UNIV SICHUAN 2011-06-01 CN claimed
CN-101724276-A Lignin modified asphalt composition with steady heat storage and preparation method thereof CHINA PETROLEUM & CHEMICAL 2010-06-09 CN claimed
CN-101654496-A Epoxy resin emulsifying agent and preparation method thereof UNIV SICHUAN 2010-02-24 CN claimed
CN-100469848-C Ultraviolet light curing coating and production thereof BYD CO LTD (CN) 2009-03-18 CN claimed
CN-100419054-C Cleaning agent for electronics equipments BELL COMM SYSTEM CO LTD (CN) 2008-09-17 CN claimed
CN-101210059-A Multipolymer resin water dispersoid containing fluorine and silicon UNIV BEIJING AVIAT & SPACEFLI (CN) 2008-07-02 CN claimed
CN-1778848-A Ultraviolet light curing coating and production thereof BIYADI CO LTD (CN) 2006-05-31 CN claimed
CN-1740153-A Prepn process of 7-ethyl tryptophol HANGZHOU KEBEN CHEMICAL CO LTD (CN) 2006-03-01 CN claimed
CN-1740154-A Prepn process of 7-ethyl tryptophol HANGZHOU KEBEN CHEMICAL CO LTD (CN) 2006-03-01 CN claimed
CN-1445352-A Cleaning agent for electronics equipments BELL COMM SYSTEM CO LTD HANGZH (CN) 2003-10-01 CN claimed
CN-1055944-A Solid gums SHEN ZHENXIN (CN) 1991-11-06 CN claimed
US-20230136194-A1 TRIAZOLOPYRIDAZINE DERIVATIVE, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF Shanghai Simr Biotechnology Co., Ltd. (CN) 2023-05-04 US disclosed
CN-110114197-A Detergent composition for plastic lens forming glass mold 花王株式会社 2019-08-09 CN disclosed
CN-108348884-A The metal dispersion of stability with raising 科莱恩国际有限公司 2018-07-31 CN disclosed
CN-1445352-A Cleaning agent for electronics equipments BELL COMM SYSTEM CO LTD HANGZH (CN) 2003-10-01 CN disclosed
US-6515112-B2 For use in diagnosis and therapy AMERSHAM PLC (GB) 2003-02-04 US disclosed
US-6001979-A AMINO-, IMINO, HYDRAZINO AND AZO SALTS OF TECHNETIUM COMPLEXED WITH NEUTRAL LIGANDS NYCOMED AMERSHAM PLC (GB) 1999-12-14 US disclosed
CN-1055944-A Solid gums SHEN ZHENXIN (CN) 1991-11-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230136194-A1 TRIAZOLOPYRIDAZINE DERIVATIVE, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF ABCG2, CYP4F8, CYP3A5 ALDH1A1 440/4885HSD17B10 2047/4885TSHR 2486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.