Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185256 | 0.75 | DDIT3 (0.49) | LIPEMAPTALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL6560775 | 0.74 | CYP4F2 (0.56) | MAPTALDH1A1CYP4F2CYP4A11GAA | |
| SCHEMBL185497 | 0.73 | LIPE (0.47) | LIPEMAPTALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL4113212 | 0.71 | CYP4F2 (0.76) | MAPTALDH1A1CYP4F2CYP4A11GAA | |
| SCHEMBL23278546 | 0.70 | MAPT (0.51) | LIPEMAPTALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL25379342 | 0.70 | LIPE (0.50) | LIPEMAPTALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL1808783 | 0.69 | LIPE (0.49) | LIPEMAPTALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL1808785 | 0.69 | LIPE (0.49) | LIPEMAPTALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL10889223 | 0.69 | CYP4F2 (0.41) | LIPEMAPTALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL2650247 | 0.69 | MAPT (0.78) | LIPEMAPTALDH1A1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020357-A1 | ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS LTD. (IN) | 2012-02-16 | — | — | WO | disclosed |