Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.56 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8362736 | 0.84 | CYP4F2 (0.39) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL833396 | 0.83 | IDO1 (0.46) | CYP4F2CYP4A11ALDH1A1MAPTLMNA | |
| SCHEMBL9071818 | 0.83 | CYP4Z1 (0.49) | CYP4F2CYP4A11ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL4113212 | 0.82 | CYP4F2 (0.76) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL12750993 | 0.80 | SLC7A5 (0.50) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL11168267 | 0.79 | POLB (0.46) | CYP4F2CYP4A11ALDH1A1GAALMNA | |
| SCHEMBL2651751 | 0.79 | CA2 (0.52) | ALDH1A1GAAMAPTLMNAKDM4E | |
| SCHEMBL7433303 | 0.76 | CYP4F2 (0.53) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL7646565 | 0.76 | CYP4F2 (0.61) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL4613929 | 0.75 | CYP4F2 (0.66) | CYP4F2CYP4A11ALDH1A1GAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169312-B1 | GLUCOKINASE ACTIVATORS | HOFFMANN LA ROCHE (CH) | 2004-10-06 | — | — | EP | disclosed |