Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 3/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15443664 | 0.88 | KDM4E (0.37) | KDM4EHSD17B10LMNAPIK3CAPIK3CB | |
| SCHEMBL10147390 | 0.87 | MAOB (0.34) | CYP19A1KDM4ECYP1A2HSD17B10ALDH1A1 | |
| SCHEMBL10118794 | 0.86 | KDM4E (0.33) | KDM4EHSD17B10LMNAMAPT | |
| SCHEMBL21142776 | 0.85 | TRPV1 (0.36) | KDM4EHSD17B10LMNAPIK3CAPIK3CB | |
| SCHEMBL2756729 | 0.83 | MMP12 (0.36) | CYP19A1KDM4EMMP12TERTMAPT | |
| SCHEMBL15443662 | 0.79 | KDM4E (0.32) | KDM4EPIK3CA | |
| SCHEMBL10141065 | 0.78 | TGFBR1 (0.37) | CYP19A1KDM4EMMP12TERTHSD17B10 | |
| SCHEMBL10147704 | 0.78 | MMP12 (0.33) | CYP19A1KDM4EMMP12TERTHSD17B10 | |
| SCHEMBL15443735 | 0.78 | PIK3CA (0.33) | KDM4EPIK3CAPIK3CBPIK3CG | |
| SCHEMBL13561501 | 0.76 | KDM4E (0.44) | KDM4ECYP1A2HSD17B10LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120076755-A1 | Hepatitis C Virus Inhibitors | ENANTA PHARMACEUTICALS, INC. | 2012-03-29 | — | — | US | disclosed |
| US-20120039848-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120039848-A1 | HEPATITIS C VIRUS INHIBITORS | HAVCR2, SLC10A1, EIF2AK2 | CYP19A1 1135/4885KDM4E 1193/4885MMP12 1729/4885 |
| US-20120076755-A1 | Hepatitis C Virus Inhibitors | NSUN2, HCCS, HAVCR2 | CYP19A1 1616/4885KDM4E 1318/4885MMP12 3344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.