SCHEMBL1014238

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3940201	0.86	RORC (0.65)	RORCCSNK2A1KMOCENPEPDK1
	SCHEMBL403840	0.86	RORC (0.56)	RORCCSNK2A1KMOCENPEKMT2A
	SCHEMBL2104888	0.85	RORC (0.55)	RORCCSNK2A1KMOCENPEPDK1
	SCHEMBL25139527	0.85	RORC (0.55)	RORCCSNK2A1KMOCENPEPDK1
	SCHEMBL1015712	0.83	RORC (0.57)	RORCCSNK2A1KMOCENPEPDK1
	SCHEMBL1980673	0.83	CA12 (0.54)	RORCCSNK2A1KMOCENPEPDK1
	SCHEMBL2536671	0.83	TSHR (0.47)	RORCPDK1KCNQ3KCNQ2TAS1R3
	SCHEMBL1013113	0.83	MAPT (0.50)	KMT2AMEN1LMNASMN1; SMN2S1PR3
	SCHEMBL16951316	0.82	RORC (0.55)	RORCCSNK2A1KMOCENPEPDK1
	SCHEMBL7353148	0.81	PDE4B (0.54)	PDK1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.