SCHEMBL10143149

SCHEMBL10143149

CCNC1=NCCO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11123493 0.87
SCHEMBL11125378 0.83
SCHEMBL4401199 0.81 ADRA2A (0.45)
SCHEMBL1726232 0.78 SMN1; SMN2 (0.43)
SCHEMBL24533674 0.77
SCHEMBL32681385 0.77 ADRA2A (0.43)
SCHEMBL23613101 0.77 ADRA2A (0.39)
SCHEMBL8707780 0.77 SMN1; SMN2 (0.42)
SCHEMBL11123146 0.77 SMN1; SMN2 (0.42)
SCHEMBL11123645 0.77 SMN1; SMN2 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240270912-A1 Water-Soluble Films and Methods of Use CMC Group, Inc. 2024-08-15 US disclosed
US-20240226113-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF KUMQUAT BIOSCIENCES INC. 2024-07-11 US disclosed
US-20240207306-A1 COMPOSITION CONTROLLING PHARMACOKINETICS IN THE BODY KAWASAKI INSTITUTE OF INDUSTRIAL PROMOTION (JP) 2024-06-27 US disclosed
US-20240207306-A1 COMPOSITION CONTROLLING PHARMACOKINETICS IN THE BODY KAWASAKI INSTITUTE OF INDUSTRIAL PROMOTION (JP) 2024-06-27 US disclosed
EP-4388070-A1 WATER-SOLUBLE FILMS AND METHODS OF USE Nohbo, Inc. (US) 2024-06-26 EP disclosed
CN-118206745-A Compounds and blocking agents comprising the same 菲鹏生物股份有限公司 2024-06-18 CN disclosed
CN-118139961-A Water-soluble films and methods of use 诺赫博股份有限公司 2024-06-04 CN disclosed
US-20230398140-A1 OCULAR-TENSION-INCREASING AGENT CAPABLE OF BEING DEPRIVED OF DRUG ACTIVITY BY TEMPERATURE CONTROL UNIVERSITY OF YAMANASHI (JP) 2023-12-14 US disclosed
US-20230398140-A1 OCULAR-TENSION-INCREASING AGENT CAPABLE OF BEING DEPRIVED OF DRUG ACTIVITY BY TEMPERATURE CONTROL UNIVERSITY OF YAMANASHI (JP) 2023-12-14 US disclosed
US-20230295139-A1 SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS UNIVERSITY OF KWAZULU-NATAL (ZA) 2023-09-21 US disclosed
US-7312235-B2 Benzamide inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. (US) 2007-12-25 US disclosed
US-7312235-B2 Benzamide inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. (US) 2007-12-25 US disclosed
US-7285565-B2 Benzamides and related inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. (US) 2007-10-23 US disclosed
US-7285565-B2 Benzamides and related inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. (US) 2007-10-23 US disclosed
US-7262186-B2 Substituted pyrazolo[3,4-d] pyrimidinones as a mitotic kinesin inhibitor MERCK & CO., INC. (US) 2007-08-28 US disclosed
US-20070021472-A1 N-(5-bromo-2-pyridinyl)-(2-4-[(2-aminosulfonyl)phenyl]phenylcarbonylamino)phenylcarboxamide; potent and highly selective inhibitors; coagulation disorders; antithrombotic agents; diagnostic reagents; good bioavailability and/or solubility MILLENNIUM PHARMACEUTICALS, INC. 2007-01-25 US disclosed
US-20070021472-A1 N-(5-bromo-2-pyridinyl)-(2-4-[(2-aminosulfonyl)phenyl]phenylcarbonylamino)phenylcarboxamide; potent and highly selective inhibitors; coagulation disorders; antithrombotic agents; diagnostic reagents; good bioavailability and/or solubility MILLENNIUM PHARMACEUTICALS, INC. 2007-01-25 US disclosed
EP-0030350-B1 METHOD FOR REDUCING THE TERMINAL CARBOXYL GROUP CONTENT OF A SATURATED POLYESTER, A SATURATED POLYESTER HAVING A REDUCED TERMINAL CARBOXYL GROUP CONTENT, AND A MOLDED ARTICLE COMPOSED OF SUCH A SATURATED POLYESTER TEIJIN LIMITED (JP) 1984-10-10 EP disclosed
US-4351936-A COMPRISING ENDCAPPING WITH AN OXAZOLINE OR OXAZINE TEIJIN LIMITED (JP) 1982-09-28 US disclosed
EP-0030350-A1 Method for reducing the terminal carboxyl group content of a saturated polyester, a saturated polyester having a reduced terminal carboxyl group content, and a molded article composed of such a saturated polyester TEIJIN LIMITED (JP) 1981-06-17 EP disclosed