Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.33 |
| ▸ | MEF2D | Q14814 | 4/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.31 |
| ▸ | F2R | P25116 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143784 | 0.90 | CA1 (0.37) | HDAC4SIRT5HDAC1 | |
| SCHEMBL10143783 | 0.84 | CA1 (0.35) | HDAC4SIRT5HDAC1 | |
| SCHEMBL10143366 | 0.83 | AR (0.37) | HDAC4MEF2DEP300 | |
| SCHEMBL10143365 | 0.83 | AR (0.35) | FPR2 | |
| SCHEMBL10144457 | 0.82 | CA1 (0.37) | HDAC4SIRT5FPR2HDAC1 | |
| SCHEMBL10144436 | 0.82 | CPB2 (0.40) | — | |
| SCHEMBL10144208 | 0.78 | TLR2 (0.40) | HDAC4MEF2DEP300SIRT5SIRT1 | |
| SCHEMBL10144324 | 0.77 | TLR2 (0.44) | HDAC4MEF2DEP300 | |
| SCHEMBL10144454 | 0.76 | CA1 (0.36) | HDAC4SIRT5HDAC1 | |
| SCHEMBL10144209 | 0.76 | TLR2 (0.39) | SIRT5FPR2SIRT1SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |