Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.35 |
| ▸ | HTRA1 | Q92743 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143783 | 0.94 | CA1 (0.35) | CA1CA2PARP1SIRT5HTRA1 | |
| SCHEMBL10144457 | 0.93 | CA1 (0.37) | CA1CA2PARP1SIRT5HTRA1 | |
| SCHEMBL10143364 | 0.90 | CTSL (0.33) | SIRT5HDAC4HDAC1 | |
| SCHEMBL10144454 | 0.86 | CA1 (0.36) | CA1CA2PARP1SIRT5HTRA1 | |
| SCHEMBL10144194 | 0.86 | MDM2 (0.39) | CA1CA2PARP1SIRT5HTRA1 | |
| SCHEMBL10144152 | 0.86 | MDM2 (0.38) | CA1CA2PARP1SIRT5HDAC4 | |
| SCHEMBL10144210 | 0.84 | MDM2 (0.40) | CA1CA2PARP1SIRT5HDAC4 | |
| SCHEMBL10143366 | 0.84 | AR (0.37) | HDAC4 | |
| SCHEMBL10144436 | 0.83 | CPB2 (0.40) | — | |
| SCHEMBL10144442 | 0.82 | CA1 (0.45) | CA1CA2PARP1SIRT5HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |