Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 15/20 | 1.00 |
| ▸ | GALR1 | P47211 | 7/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | APAF1 | O14727 | 1/20 | 0.55 |
| ▸ | NSD2 | O96028 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.55 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144339 | 0.90 | GALR2 (0.82) | GALR2GALR1MAPK1TAAR1MAPT | |
| SCHEMBL3240927 | 0.87 | GALR2 (0.77) | GALR2GALR1MAPTAPAF1GAA | |
| SCHEMBL10143796 | 0.85 | GALR2 (1.00) | GALR2GALR1MAPK1TAAR1MAPT | |
| SCHEMBL10144392 | 0.83 | GALR2 (1.00) | GALR2GALR1MAPK1TAAR1MAPT | |
| SCHEMBL10143418 | 0.83 | GALR2 (0.86) | GALR2GALR1MAPK1TAAR1MAPT | |
| SCHEMBL23221587 | 0.80 | GALR2 (0.66) | GALR2GALR1MAPK1TAAR1MAPT | |
| SCHEMBL3240515 | 0.79 | GALR2 (0.64) | GALR2GALR1MAPK1TAAR1MAPT | |
| SCHEMBL10144388 | 0.78 | GALR2 (1.00) | GALR2GALR1MAPK1TAAR1MAPT | |
| SCHEMBL18162430 | 0.78 | GALR2 (0.64) | GALR2GALR1MAPK1TAAR1MAPT | |
| SCHEMBL10144177 | 0.78 | GALR2 (0.82) | GALR2GALR1MAPK1TAAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |