Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | PKM | P14618 | 4/20 | 0.58 |
| ▸ | PKLR | P30613 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18063485 | 0.88 | KMT2A (0.84) | KMT2APKMPKLRNPC1RAB9A | |
| SCHEMBL10143452 | 0.85 | KMT2A (0.56) | KMT2APKMPKLRNPC1RAB9A | |
| SCHEMBL18162505 | 0.82 | KMT2A (0.60) | KMT2APKMPKLRNPC1RAB9A | |
| SCHEMBL18087218 | 0.82 | KMT2A (1.00) | KMT2APKMPKLRNPC1RAB9A | |
| SCHEMBL18153330 | 0.80 | KMT2A (0.61) | KMT2APKMPKLRNPC1RAB9A | |
| SCHEMBL5327466 | 0.80 | PKM (0.59) | KMT2APKMPKLRNPC1RAB9A | |
| SCHEMBL10143454 | 0.80 | KMT2A (0.60) | KMT2APKMPKLRNPC1RAB9A | |
| SCHEMBL18063487 | 0.78 | KMT2A (0.82) | KMT2APKMPKLRNPC1RAB9A | |
| SCHEMBL23221425 | 0.77 | KMT2A (0.84) | KMT2APKMPKLRNPC1RAB9A | |
| SCHEMBL18153365 | 0.76 | KMT2A (0.79) | KMT2APKMPKLRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |