Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 5/20 | 0.54 |
| ▸ | PKLR | P30613 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143454 | 0.96 | KMT2A (0.60) | KMT2APKMPKLRNPC1RAB9A | |
| SCHEMBL10143456 | 0.85 | KMT2A (0.69) | KMT2APKMPKLRNPC1RAB9A | |
| SCHEMBL10143440 | 0.81 | KMT2A (0.54) | KMT2APKMPKLRNPC1RAB9A | |
| SCHEMBL5327466 | 0.77 | PKM (0.59) | KMT2APKMPKLRNPC1RAB9A | |
| SCHEMBL18063485 | 0.76 | KMT2A (0.84) | KMT2APKMPKLRNPC1RAB9A | |
| SCHEMBL1044915 | 0.74 | HTT (0.96) | KMT2APKMPKLRNPC1RAB9A | |
| SCHEMBL31315853 | 0.74 | PKM (1.00) | KMT2APKMPKLRNPC1RAB9A | |
| SCHEMBL1722721 | 0.74 | PKM (1.00) | KMT2APKMPKLRNPC1RAB9A | |
| SCHEMBL10143752 | 0.72 | TP53 (0.52) | KMT2AHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL4555472 | 0.72 | HTT (1.00) | KMT2APKMPKLRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |