Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144432 | 0.91 | CA1 (0.45) | MDM2CA1CA2TPSAB1SIRT5 | |
| SCHEMBL10144428 | 0.90 | TLR2 (0.42) | MDM2TPSAB1 | |
| SCHEMBL10143500 | 0.89 | SIRT5 (0.42) | MDM2CA1CA2TPSAB1SIRT5 | |
| SCHEMBL10144419 | 0.89 | MDM2 (0.41) | MDM2CA1CA2CCKBRTPSAB1 | |
| SCHEMBL10143496 | 0.88 | CA1 (0.42) | MDM2CA1CA2TPSAB1SIRT5 | |
| SCHEMBL10144194 | 0.86 | MDM2 (0.39) | MDM2CA1CA2TPSAB1SIRT5 | |
| SCHEMBL10143498 | 0.86 | MDM2 (0.41) | CTSSMDM2CA1CA2SIRT5 | |
| SCHEMBL10144152 | 0.85 | MDM2 (0.38) | MDM2CA1CA2TPSAB1SIRT5 | |
| SCHEMBL10143509 | 0.85 | CACNA1B (0.39) | MDM2CA1CA2TPSAB1SIRT5 | |
| SCHEMBL10144210 | 0.84 | MDM2 (0.40) | CTSSCTSKMDM2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |