Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.81 |
| ▸ | CASP1 | P29466 | 5/20 | 0.61 |
| ▸ | CASP5 | P51878 | 5/20 | 0.61 |
| ▸ | CASP4 | P49662 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10377525 | 0.98 | HRH4 (0.78) | HRH4CASP1CASP5CASP4SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11268605 | 0.96 | HRH4 (0.76) | HRH4CASP1CASP5CASP4SMN1; SMN2 | |
| SCHEMBL8891695 | 0.88 | CASP1 (0.78) | HRH4CASP1CASP5CASP4SMN1; SMN2 | |
| SCHEMBL8900887 | 0.88 | CASP1 (0.78) | HRH4CASP1CASP5CASP4SMN1; SMN2 | |
| SCHEMBL10377507 | 0.87 | HRH4 (0.62) | HRH4CASP1CASP5CASP4SMN1; SMN2 | |
| SCHEMBL1458548 | 0.85 | HRH4 (0.61) | HRH4CASP1CASP5CASP4SMN1; SMN2 | |
| SCHEMBL30296930 | 0.85 | HRH4 (0.61) | HRH4CASP1CASP5CASP4SMN1; SMN2 | |
| SCHEMBL29754406 | 0.85 | CASP1 (0.80) | HRH4CASP1CASP5CASP4SMN1; SMN2 | |
| SCHEMBL10375476 | 0.83 | HRH4 (0.59) | HRH4CASP1CASP5CASP4HRH3 | |
| SCHEMBL3289509 | 0.83 | KMT2A (0.65) | HRH4SMN1; SMN2CRHBPCRHR2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |