Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 3/20 | 0.78 |
| ▸ | CASP5 | P51878 | 3/20 | 0.78 |
| ▸ | CASP4 | P49662 | 2/20 | 0.78 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | HRH1 | P35367 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.43 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900887 | 1.00 | CASP1 (0.78) | CASP1CASP5CASP4HRH4SMN1; SMN2 | |
| SCHEMBL10377525 | 0.90 | HRH4 (0.78) | CASP1CASP5CASP4HRH4SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11268605 | 0.89 | HRH4 (0.76) | CASP1CASP5CASP4HRH4SMN1; SMN2 | |
| SCHEMBL6505711 | 0.88 | CASP1 (1.00) | CASP1CASP5CASP4HRH4SMN1; SMN2 | |
| SCHEMBL9492704 | 0.88 | CASP1 (1.00) | CASP1CASP5CASP4HRH4SMN1; SMN2 | |
| SCHEMBL10143607 | 0.88 | HRH4 (0.81) | CASP1CASP5CASP4HRH4SMN1; SMN2 | |
| SCHEMBL7773886 | 0.85 | CASP1 (0.93) | CASP1CASP5CASP4HRH4SMN1; SMN2 | |
| SCHEMBL8962166 | 0.81 | CASP1 (0.77) | CASP1CASP5CASP4HRH4SMN1; SMN2 | |
| SCHEMBL9545737 | 0.79 | CASP1 (0.81) | CASP1CASP5CASP4HRH4SMN1; SMN2 | |
| SCHEMBL7777439 | 0.79 | HRH4 (0.78) | CASP1CASP5CASP4HRH4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997014685-A1 | PYRIMIDINE DERIVATIVES | GYÓGYSZERKUTATÓ INTÉZET KFT (HU) | 1997-04-24 | — | — | WO | disclosed |