Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 16/20 | 0.77 |
| ▸ | GALR1 | P47211 | 8/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143412 | 0.96 | GALR2 (0.74) | GALR2GALR1MAPK1TAAR1KDM4E | |
| SCHEMBL10144392 | 0.88 | GALR2 (1.00) | GALR2GALR1MAPK1TAAR1KDM4E | |
| SCHEMBL10144345 | 0.87 | GALR2 (0.71) | GALR2GALR1KDM4EALDH1A1HPGD | |
| SCHEMBL10143419 | 0.86 | GALR2 (0.81) | GALR2GALR1MAPK1TAAR1KDM4E | |
| SCHEMBL10143796 | 0.82 | GALR2 (1.00) | GALR2GALR1MAPK1TAAR1ALDH1A1 | |
| SCHEMBL10144390 | 0.81 | GALR2 (0.81) | GALR2GALR1MAPK1TAAR1GBA1 | |
| SCHEMBL10143409 | 0.81 | GALR2 (0.82) | GALR2GALR1MAPK1TAAR1GBA1 | |
| SCHEMBL10144388 | 0.80 | GALR2 (1.00) | GALR2GALR1MAPK1TAAR1GBA1 | |
| SCHEMBL10143418 | 0.80 | GALR2 (0.86) | GALR2GALR1MAPK1TAAR1KDM4E | |
| SCHEMBL10144177 | 0.80 | GALR2 (0.82) | GALR2GALR1MAPK1TAAR1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |