Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | GALR2 | O43603 | 1/20 | 0.54 |
| ▸ | GALR1 | P47211 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | CCNK | O75909 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | CCND3 | P30281 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.48 |
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30675103 | 0.85 | GALR2 (0.48) | MAPTMEN1KMT2AMAPK1TDP1 | |
| SCHEMBL10143436 | 0.83 | GALR2 (0.64) | MAPTMEN1KMT2AMAPK1TDP1 | |
| SCHEMBL10143493 | 0.83 | GALR1 (0.74) | MAPTMEN1KMT2AMAPK1TDP1 | |
| SCHEMBL10143663 | 0.82 | GALR2 (0.51) | MAPTMEN1KMT2AMAPK1TDP1 | |
| SCHEMBL6234182 | 0.82 | MAPT (0.53) | MAPTKMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL30675091 | 0.82 | GALR2 (0.46) | MAPTMEN1KMT2AMAPK1TDP1 | |
| SCHEMBL15879042 | 0.79 | MEN1 (0.50) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL1409174 | 0.79 | GPR119 (0.49) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14387482 | 0.79 | MEN1 (0.50) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL17630268 | 0.76 | CCND3 (0.63) | MAPTMEN1KMT2ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |